Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17713229 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL336160 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL436299 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL15224 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL3765761 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL5431049 | 1.00 | TSHR (0.60) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL9618569 | 0.98 | TSHR (0.59) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL828469 | 0.95 | TSHR (0.67) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL7078308 | 0.95 | TSHR (0.67) | TSHRALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL828217 | 0.95 | TSHR (0.67) | TSHRALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070007197-A1 | System and method for synthesizing a polymeric membrane | MAHENDRAN MAILVAGANAM | 2007-01-11 | — | — | US | claimed |
| WO-2005037917-A1 | SYSTEM AND METHOD FOR SYNTHESIZING A POLYMER MEMBRANE | ZENON ENVIRONMENTAL INC. (CA) | 2005-04-28 | — | — | WO | claimed |
| US-20140228135-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | KYODO YUSHI CO., LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20100323934-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | NTN CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20080081873-A1 | Thermoplastic Elastomer Composition And Method For Producing Same | JSR CORPORATION (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1816163-A1 | THERMOPLASTIC ELASTOMER COMPOSITION AND METHOD FOR PRODUCING SAME | JSR Corporation (JP) | 2007-08-08 | — | — | EP | disclosed |