SCHEMBL3773140

SCHEMBL3773140

Nc1nc(-n2cnnc2)c2nc[nH]c2n1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 3/20 0.33
PDPK1 O15530 1/20 0.33
GDA Q9Y2T3 1/20 0.33
CDK2 P24941 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324270 0.83 HRH4 (0.33) HRH4PDPK1GDACDK2DPP4
SCHEMBL3780109 0.81 ADORA2A (0.40) HRH4
SCHEMBL17364330 0.78 ADORA2A (0.40) HRH4DPP4
SCHEMBL562492 0.77 HTT (0.31)
SCHEMBL8830247 0.75 CHUK (0.48) HRH4
SCHEMBL8826198 0.75 HRH4 (0.50) HRH4
SCHEMBL8830437 0.74 CHUK (0.50) HRH4
SCHEMBL8826309 0.74 CHUK (0.50) HRH4
SCHEMBL3773144 0.73 HRH4 (0.56) HRH4PDPK1GDACDK2DPP4
SCHEMBL22401491 0.73 HRH4 (0.57) HRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7855285-B2 Methods for selective N-9 glycosylation of purines BRIGHAM YOUNG UNIVERSITY (US) 2010-12-21 US disclosed
US-20080207891-A1 Methods For Selective N-9 Glycosylation of Purines BRIGHAM YOUNG UNIVERSITY (US) 2008-08-28 US disclosed
EP-1895841-A2 METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES Brigham Young University (US) 2008-03-12 EP disclosed
WO-2006138396-A2 METHODS FOR SELECTIVE N-9 GLYCOSYLATION OF PURINES BRIGHAM YOUNG UNIVERSITY, TRANSFER TECHNOLOGY OFFICE (US) 2006-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207891-A1 Methods For Selective N-9 Glycosylation of Purines PNP, SLC29A2, SLC28A2 HRH4 3326/4885PDPK1 3495/4885GDA 166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.