SCHEMBL3774446

SCHEMBL3774446

C=CCC(C)(C)CCCCC

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.42
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.32
FDPS P14324 9/20 0.31
GGPS1 O95749 6/20 0.31
FAAH O00519 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27879310 0.98 TSHR (0.46) TSHRALDH1A1THRBFDPSGGPS1
SCHEMBL9585050 0.98 TSHR (0.46) TSHRALDH1A1THRBFDPSGGPS1
SCHEMBL4733861 0.98 TSHR (0.46) TSHRALDH1A1THRBFDPSGGPS1
Hydrochloric Acid SCHEMBL28154624 0.94 TSHR (0.43) TSHRALDH1A1THRBFDPSGGPS1
SCHEMBL11597720 0.93 TSHR (0.42) TSHRALDH1A1
SCHEMBL9056413 0.84 TSHR (0.35) TSHR
SCHEMBL3292585 0.82
SCHEMBL11093025 0.82 TSHR (0.39) TSHRALDH1A1FDPSGGPS1FAAH
SCHEMBL8960454 0.81
SCHEMBL3669175 0.81 TSHR (0.42) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 US claimed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 US claimed
US-12006282-B2 Continuous hydroformylation process with catalyst substitution OQ CHEMICALS GMBH (DE) 2024-06-11 US disclosed
EP-3770144-B1 CONTINUOUS HYDROFORMYLATION PROCESS WITH CATALYST SUBSTITUTION OQ CHEMICALS GMBH (DE) 2023-09-06 EP disclosed
EP-4112599-A1 KEY INTERMEDIATE FOR SYNTHESIZING PROSTAGLANDIN COMPOUNDS AND PREPARATION METHOD THEREFOR SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) 2023-01-04 EP disclosed
US-20220371979-A1 Continuous Hydroformylation Process With Catalyst Substitution OQ CHEMICALS GMBH (DE) 2022-11-24 US disclosed
WO-2021013848-A1 CONTINUOUS HYDROFORMYLATION PROCESS WITH CATALYST SUBSTITUTION OQ CHEMICALS GMBH (DE) 2021-01-28 WO disclosed
EP-3770144-A1 CONTINUOUS HYDROFORMYLATION PROCESS WITH CATALYST SUBSTITUTION OQ Chemicals GmbH (DE) 2021-01-27 EP disclosed
WO-2017017146-A1 COMPOSITIONS CONTAINING POLYANION, ETHOXYLATED CATIONIC POLYMER AND PHYLLOSILICATES FOR IMPROVED OXYGEN BARRIER COATINGS BASF SE (DE) 2017-02-02 WO disclosed
US-9272986-B2 Diacylhydrazine ligands for modulating the expression of exogenous genes in mammalian systems via an ecdysone receptor complex INTREXON CORPORATION (US) 2016-03-01 US disclosed
US-20150005256-A1 Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes in Mammalian Systems via an Ecdysone Receptor Complex INTREXON CORP (US) 2015-01-01 US disclosed
CN-85105099-A The method for preparing aldehyde 1986-12-31 CN disclosed
US-4593126-A Reacting an olefin with carbon monoxide and hydrogen RUHRCHEMIE AKTIENGESELLSCHAFT (DE) 1986-06-03 US disclosed
EP-0160249-A2 Process for the preparation of aldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1985-11-06 EP disclosed
EP-0158246-A2 Process for the production of aldehydes Ruhrchemie Aktiengesellschaft (DE) 1985-10-16 EP disclosed
EP-0149894-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1985-07-31 EP disclosed
US-RE31812-E TO ALDEHYDES IN PRESENCE OF CATALYTIC SYSTEM CONTAINING RHODIUM AND SULFONATED ARYL PHOSPHINE COMPOUND RHONE-POULENC INDUSTRIES (FR) 1985-01-22 US disclosed
EP-0096987-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1983-12-28 EP disclosed
EP-0096986-A2 Hydroformylation process DAVY McKEE (LONDON) LIMITED (GB) 1983-12-28 EP disclosed
US-4248802-A Catalytic hydroformylation of olefins RHONE-POULENC INDUSTRIES (FR) 1981-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220371979-A1 Continuous Hydroformylation Process With Catalyst Substitution CYP4F3, CYP4F2, CYP2F1 TSHR 1960/4885ALDH1A1 2642/4885THRB 876/4885
US-12006282-B2 Continuous hydroformylation process with catalyst substitution CYP4F3, CYP4F2, CYP2F1 TSHR 1960/4885ALDH1A1 2642/4885THRB 876/4885
US-20150005256-A1 Diacylhydrazine Ligands for Modulating the Expression of Exogenous Genes in Mammalian Systems via an Ecdysone Receptor Complex NR2E3, NR2C2, NR5A2 TSHR 547/4885ALDH1A1 3743/4885THRB 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.