⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17635568 | 1.00 | — | — | |
| SCHEMBL1743874 | 0.72 | — | — | |
| SCHEMBL1039276 | 0.70 | — | — | |
| SCHEMBL23367 | 0.70 | — | — | |
| SCHEMBL3661818 | 0.70 | — | — | |
| SCHEMBL8637388 | 0.70 | — | — | |
| SCHEMBL29365 | 0.67 | — | — | |
| SCHEMBL12487242 | 0.67 | — | — | |
| SCHEMBL2126231 | 0.67 | — | — | |
| SCHEMBL997893 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107174665-A | Solid pharmaceutical preparation and its production method containing alkylcellulose | 信越化学工业株式会社 | 2017-09-19 | — | — | CN | disclosed |
| US-9200276-B2 | Polynucleotides for multivalent RNA interference, compositions and methods of use thereof | HALO-BIO RNAI THERAPEUTICS, INC. (US) | 2015-12-01 | — | — | US | disclosed |
| US-9018387-B2 | Complexes of imidazole ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2015-04-28 | — | — | US | disclosed |
| US-8680289-B2 | Complexes of imidazole ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| CN-101583601-B | As melatonin receptor MT1And MT2Isoquinolone compounds of subtype selective agonists of | UNIV HONG KONG SCIENCE & TECHN | 2013-06-05 | — | — | CN | disclosed |
| US-20130078391-A1 | Complexes Of Imidazole Ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2013-03-28 | — | — | US | disclosed |
| US-8389544-B2 | Isoquinolone compounds as subtype-selective agonists for melatonin receptors MT1 and MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2013-03-05 | — | — | US | disclosed |
| US-20120121806-A1 | Complexes Of Imidazole Ligands | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20100317691-A1 | ISOQUINOLONE COMPOUNDS AS SUBTYPE-SELECTIVE AGONISTS FOR MELATONIN RECEPTORS MT1 AND MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-12-16 | — | — | US | disclosed |
| CN-101583601-A | As melatonin receptor MT1And MT2Isoquinolone compounds of subtype selective agonists of | UNIV HONG KONG SCIENCE & TECHN (HK) | 2009-11-18 | — | — | CN | disclosed |
| WO-2008092292-A1 | ISOQUINOLONE COMPOUNDS AS SUBTYPE-SELECTIVE AGONISTS FOR MELATONIN RECEPTORS MT1 AND MT2 | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2008-08-07 | — | — | WO | disclosed |
| EP-1288196-A1 | Process for the preparation of organo guanidinium salts | Chordip Ltd. (GB) | 2003-03-05 | — | — | EP | disclosed |
| CN-1322765-A | Prepn of polyvinyl chloride resin with very low degree of polymerization | SHANGHAI LUJIAN CHEMICAL CO LT (CN) | 2001-11-21 | — | — | CN | disclosed |