SCHEMBL3775773

SCHEMBL3775773

O=C1CCC(=O)OC(=O)CCC(=O)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 1.00
LMNA P02545 2/20 0.47
TP53 P04637 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CA1 P00915 2/20 0.35
CA9 Q16790 2/20 0.35
KDM4E B2RXH2 2/20 0.34
CYP1A2 P05177 1/20 0.34
GLA P06280 1/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
CYP2C19 P33261 1/20 0.34
SIRT1 Q96EB6 1/20 0.34
HSD17B10 Q99714 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.32
GMNN O75496 1/20 0.32
PPM1B O75688 1/20 0.32
PPP1CC P36873 1/20 0.32
TFPI2 P48307 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1333224 1.00
SCHEMBL1330876 1.00
SCHEMBL16123 1.00
SCHEMBL3948099 1.00 TSHR (1.00) TSHRLMNATP53ALDH1A1CA1
SCHEMBL10783338 0.96
SCHEMBL991942 0.96
Ammonia Solution, Strong SCHEMBL1484118 0.96
Bromide SCHEMBL2163421 0.96 TSHR (0.92) TSHRLMNATP53ALDH1A1CA1
SCHEMBL6234733 0.96
SCHEMBL1014110 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956985-B Method for preparing 2, 5-dihydroxyterephthalic acid by oxygen oxidation 天津科技大学 2023-10-20 CN claimed
CN-115433084-A Method for preparing 2, 5-dihydroxy terephthalic acid dialkyl ester by continuous flow oxidation 天津科技大学 2022-12-06 CN claimed
EP-3455298-B1 QUINACRIDONE PIGMENT AND A PROCESS FOR PREPARATION THEREOF GHARDA KEKI HORMUSJI (IN) 2022-10-26 EP claimed
CN-114956985-A Method for preparing 2, 5-dihydroxy terephthalic acid by oxygen oxidation 天津科技大学 2022-08-30 CN claimed
CN-110615743-A Lyotropic color-changing fluorescent compound and preparation method and application thereof 天津科技大学 2019-12-27 CN claimed
CN-104276953-B A kind of method preparing 1,4 cyclohexanedicarboxylic acid diester DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2016-03-23 CN claimed
CN-104276953-A Method for preparing dialkyl 1,4-cyclohexanedicarboxylate DALIAN CHEMICAL PHYSICS INST 2015-01-14 CN claimed
CN-119424750-A Medical dura mater (spinal) membrane repair hydrogel and kit 天津市康尔医疗器械有限公司 2025-02-14 CN disclosed
CN-220911931-U Dimethylbutanedioyl succinate production drying device 河北彩客新材料科技股份有限公司 2024-05-07 CN disclosed
WO-2023208924-A1 MIXED CRYSTAL COMPOSITION OF QUINACRIDONES WITH DIKETOPYRROLOPYRROLES AND MANUFACTURING PROCESS SUN CHEMICAL CORPORATION (US) 2023-11-02 WO disclosed
CN-114956985-B Method for preparing 2, 5-dihydroxyterephthalic acid by oxygen oxidation 天津科技大学 2023-10-20 CN disclosed
CN-116499229-B Drying equipment and process for production of dimethyl butyryl succinate 河北彩客新材料科技股份有限公司 2023-10-13 CN disclosed
CN-116499229-A Drying equipment and process for production of dimethyl butyryl succinate 河北彩客新材料科技股份有限公司 2023-07-28 CN disclosed
US-20100069927-A1 Polymeric Masking Materials for Spanning Wound Sites, and Methods of Use Thereof HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2010-03-18 US disclosed
WO-2010004377-A1 ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (US) 2010-01-14 WO disclosed
WO-2009015124-A2 POLYMERIC MASKING MATERIALS FOR SPANNING WOUND SITES, AND METHODS OF USE THEREOF HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2009-01-29 WO disclosed
CN-1823274-A Method for diagnosing endometriosis-related diseases KOSUGI YOSHINORI (JP) 2006-08-23 CN disclosed
US-4540808-A Process for the preparation of 4-alkoxyacetoacetic acid ester LONZA, LTD. (CH) 1985-09-10 US disclosed
US-4305823-A MODIFIED WITH CYCLIC B-KETONIC ACIDS CIBA-GEIGY CORPORATION (US) 1981-12-15 US disclosed
US-4249000-A SEMIPERMEABLE MEMBRANES FOR REVERSE OSMOSIS CIBA-GEIGY CORPORATION (US) 1981-02-03 US disclosed