SCHEMBL377707

SCHEMBL377707

CCCC(=O)c1ccc(OC(COc2ccc(C(F)(F)F)cc2)CSc2ccc([O])c(C)c2)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.79
PPARA Q07869 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377708 0.91 PPARD (0.79) PPARDPPARA
SCHEMBL7015392 0.90 PPARD (0.83) PPARDPPARA
SCHEMBL7018299 0.90 PPARD (0.85) PPARDPPARA
SCHEMBL377493 0.88 PPARD (1.00) PPARDPPARA
SCHEMBL14355009 0.88 PPARD (0.81) PPARDPPARA
SCHEMBL3699167 0.87 PPARD (0.85) PPARDPPARA
SCHEMBL10187704 0.85 PPARD (0.76) PPARDPPARA
SCHEMBL5438038 0.84 PPARD (0.71) PPARDPPARA
SCHEMBL377485 0.81 PPARD (0.72) PPARDPPARA
SCHEMBL377494 0.81 PPARD (0.72) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2100877-B1 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs JANSSEN PHARMACEUTICA NV (BE) 2012-01-25 EP claimed