Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 8/20 | 0.64 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | CNR1 | P21554 | 3/20 | 0.60 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27673441 | 1.00 | ESR1 (0.64) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6940194 | 0.94 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL22289842 | 0.94 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL14376406 | 0.94 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL12110051 | 0.94 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28588245 | 0.94 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29263833 | 0.94 | ESR1 (0.69) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13308500 | 0.91 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL5710040 | 0.91 | ESR1 (0.71) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL14099429 | 0.88 | ESR1 (0.64) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228135-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | KYODO YUSHI CO., LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20100323934-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | NTN CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |