SCHEMBL3777804

SCHEMBL3777804

C(OCOCC1CO1)OCC1CO1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.59
ALDH1A1 P00352 10/20 0.52
MAPK1 P28482 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 3/20 0.46
TP53 P04637 4/20 0.37
CYP3A4 P08684 2/20 0.37
HIF1A Q16665 2/20 0.37
GLA P06280 1/20 0.34
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
CYP1A2 P05177 1/20 0.32
KMT2A Q03164 1/20 0.32
PPARG P37231 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
CHRM2 P08172 1/20 0.30
CHRM5 P08912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1402498 0.97 TSHR (0.62) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL10071449 0.88 TSHR (0.48) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL10071444 0.88 TSHR (0.48) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL5574648 0.85 TSHR (0.50) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL2933673 0.84
SCHEMBL2933671 0.84
SCHEMBL4895623 0.84 TSHR (0.68) TSHRALDH1A1MAPK1SMN1; SMN2TDP1
SCHEMBL15245 0.84
SCHEMBL4623846 0.84
Bromide SCHEMBL10338450 0.81 TSHR (0.65) TSHRALDH1A1MAPK1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184652-A1 CURABLE RESINS AND ARTICLES MADE THEREFROM DIGITALOPTICS CORPORATION EAST (US) 2012-07-19 US disclosed
US-20120178859-A1 CURABLE RESINS AND ARTICLES MADE THEREFROM DIGITALOPTICS CORPORATION EAST (US) 2012-07-12 US disclosed
US-8197723-B2 Curable resins and articles made therefrom DIGITALOPTICS CORPORATION EAST (US) 2012-06-12 US disclosed
US-7855245-B2 Adhesive composition and a method of using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-21 US disclosed
WO-2010144763-A2 CURABLE RESINS AND ARTICLES MADE THEREFROM TESSERA RESEARCH LLC (US) 2010-12-16 WO disclosed
US-20100314591-A1 CURABLE RESINS AND ARTICLES MADE THEREFROM TESSERA RESEARCH LLC (US) 2010-12-16 US disclosed
WO-2010065784-A2 METHODS, DEVICES, AND COMPOSITIONS FOR DERMAL FILLING JAKK GROUP, INC. (US) 2010-06-10 WO disclosed
US-20100136070-A1 METHODS, DEVICES, AND COMPOSITIONS FOR DERMAL FILLING JAKK GROUP, INC. (US) 2010-06-03 US disclosed
US-20080268255-A1 Adhesive composition and a method of using the same SHIN-ETSU CHEMICAL CO., LTD. 2008-10-30 US disclosed
EP-0170236-A2 Polyglycidyl ethers of tricyclodecane and cured epoxy resins therefrom HENKEL CORPORATION (a Delaware corp.) (US) 1986-02-05 EP disclosed
US-4535148-A Polyglycidyl ethers of tricyclodecane and cured epoxy resins therefrom HENKEL CORPORATION (US) 1985-08-13 US disclosed