Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 6/20 | 0.33 |
| ▸ | PRKACA | P17612 | 4/20 | 0.33 |
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | PRKX | P51817 | 4/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP46A1 | Q9Y6A2 | 3/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | AKT2 | P31751 | 3/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.33 |
| ▸ | PRKG2 | Q13237 | 3/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 3/20 | 0.33 |
| ▸ | SGK2 | Q9HBY8 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3779580 | 0.91 | AHR (0.36) | GSK3BAKR1C3AKR1C2GCK | |
| SCHEMBL3780099 | 0.90 | MAP4K4 (0.36) | MAP4K4FFAR4MINK1 | |
| SCHEMBL3781398 | 0.90 | FFAR4 (0.35) | FFAR4 | |
| SCHEMBL3777917 | 0.89 | FFAR4 (0.35) | CYP46A1FFAR4 | |
| SCHEMBL3779586 | 0.88 | KDM1A (0.37) | AKT1MAP4K4MINK1 | |
| SCHEMBL3767789 | 0.85 | ECE1 (0.36) | FFAR4 | |
| SCHEMBL3771948 | 0.85 | CNR2 (0.36) | — | |
| SCHEMBL3768528 | 0.84 | SLC22A12 (0.37) | CLK4MAPK1 | |
| SCHEMBL3773302 | 0.82 | CYP4A11 (0.34) | CYP4A11CYP4F2 | |
| SCHEMBL3776531 | 0.82 | MAP4K4 (0.37) | MAP4K4FFAR4MINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | LES LABORATOIRES SERVIER (FR) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317698-A1 | Polysubstituted Pyridinylaminoalkylene- and Pyridinyloxyalkylene-Cyclopropanamine Compounds, a Process for Their Preparation and Pharmaceutical Compositions Containing Them | CHRNA6, CHRNE, CHRNG | ROCK1 2896/4885PRKACA 4040/4885GSK3A 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.