⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622738 | 0.78 | — | — | |
| SCHEMBL7488117 | 0.75 | — | — | |
| SCHEMBL443013 | 0.73 | — | — | |
| SCHEMBL27708882 | 0.72 | — | — | |
| SCHEMBL2936407 | 0.72 | — | — | |
| SCHEMBL3695368 | 0.71 | — | — | |
| SCHEMBL622307 | 0.71 | — | — | |
| SCHEMBL3692073 | 0.71 | — | — | |
| SCHEMBL442555 | 0.70 | — | — | |
| SCHEMBL27694742 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324030-A1 | 5-Quinoline derivatives having an anti-bacterial activity | MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) | 2010-12-23 | — | — | US | disclosed |
| CN-101341126-A | Antibacterial active 5-chinolin derivative | MORPHOCHEM AG FUER KOM (DE) | 2009-01-07 | — | — | CN | disclosed |
| EP-1943222-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007042325-A1 | ANTIBACTERIAL ACTIVE 5-CHINOLIN DERIVATIVE | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2007-04-19 | — | — | WO | disclosed |