SCHEMBL3782348

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3776565	0.95	RAF1 (0.84)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL5635314	0.90	RAF1 (0.86)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL3546122	0.90	RAF1 (1.00)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL3545392	0.88	RAF1 (0.90)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL16628058	0.87	RAF1 (0.75)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL15574549	0.87	RAF1 (0.70)	RAF1BRAFKDRRETPDGFRB
	SCHEMBL6030121	0.86	RAF1 (0.89)	RAF1BRAFKDRRETPDGFRB
	Sorafenib SCHEMBL14739751	0.86	RAF1 (1.00)	RAF1BRAFKDRRETPDGFRB
	Sorafenib SCHEMBL29349634	0.86	RAF1 (1.00)	RAF1BRAFKDRRETPDGFRB
	Sorafenib SCHEMBL8218	0.86	RAF1 (1.00)	RAF1BRAFKDRRETPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.