Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13240866 | 1.00 | CHRM2 (0.53) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL12014464 | 1.00 | CHRM2 (0.53) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL2484719 | 0.92 | CHRM2 (0.57) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| Trifluoroacetic Acid SCHEMBL2993843 | 0.92 | CHRM2 (0.57) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL3782038 | 0.86 | CHRM3 (0.43) | CHRM2CHRM3CHRM1CHRM4CHRM5 | |
| SCHEMBL13240912 | 0.84 | CHRM3 (0.44) | CHRM2CHRM3CHRM1MEN1KMT2A | |
| SCHEMBL16664379 | 0.84 | CHRM3 (0.44) | CHRM2CHRM3CHRM1MEN1KMT2A | |
| SCHEMBL13282731 | 0.83 | CHRM3 (0.43) | CHRM2CHRM3CHRM1 | |
| SCHEMBL16649371 | 0.82 | CHRM3 (0.55) | CHRM2CHRM3CHRM1CHRNB4CHRNA3 | |
| SCHEMBL13240902 | 0.82 | CHRM3 (0.55) | CHRM2CHRM3CHRM1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | claimed |
| WO-2012110462-A1 | LIQUID PROPELLANT-FREE FORMULATION COMPRISING AN ANTIMUSCARINIC DRUG | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-08-23 | — | — | WO | disclosed |
| EP-2206712-A1 | \"Alkaloid aminoester derivatives and medicinal composition thereof\ | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-07-14 | — | — | EP | disclosed |
| EP-2206712-A1 | \"Alkaloid aminoester derivatives and medicinal composition thereof\ | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-07-14 | — | — | EP | disclosed |