Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7105177 | 1.00 | — | — | |
| Acetic Acid SCHEMBL598589 | 1.00 | FFAR3 (0.44) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL355812 | 1.00 | FFAR3 (0.44) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL3062950 | 0.97 | GABRR1 (0.42) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL17800809 | 0.97 | GABRR1 (0.42) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL1232731 | 0.97 | GABRR1 (0.42) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL26923588 | 0.97 | GABRR1 (0.42) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL5527270 | 0.94 | GABRR1 (0.40) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL6707542 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNGABRR1LMNA | |
| Acetic Acid SCHEMBL5570292 | 0.84 | FFAR3 (0.47) | FFAR3LCKFYNGABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7857876-B2 | Method of producing polishing material comprising diamond clusters | NIHON MICRO COATING CO., LTD. (JP) | 2010-12-28 | — | — | US | disclosed |
| US-7585341-B2 | Polishing material comprising diamond clusters | NIHON MICRO COATING CO., LTD. (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20090188170-A1 | METHOD OF PRODUCING POLISHING MATERIAL COMPRISING DIAMOND CLUSTERS | NIHON MICRO COATING CO., LTD. (JP) | 2009-07-30 | — | — | US | disclosed |
| EP-1944347-A1 | ABRASIVE MATERIAL AND PROCESS FOR PRODUCING THE SAME | Nihon Microcoating Co., Ltd. (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20070231245-A1 | Polishing material and production method therefor | NIHON MICRO COATING CO., LTD. | 2007-10-04 | — | — | US | disclosed |