Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3792043 | 0.84 | KDM4E (0.45) | TP53MAPTAURKBAURKAHPGD | |
| SCHEMBL5455186 | 0.74 | PDE4B (0.74) | TP53MAPTPDE4BCREBBP | |
| SCHEMBL23493909 | 0.73 | MAPT (0.85) | TP53MAPTAURKBAURKAPDE4B | |
| SCHEMBL31307824 | 0.73 | MAPT (0.85) | TP53MAPTAURKBAURKAPDE4B | |
| SCHEMBL5409568 | 0.72 | PDE4B (0.54) | TP53MAPTPDE4BTERT | |
| SCHEMBL5325636 | 0.70 | CREBBP (0.79) | TP53MAPTAURKBAURKAPDE4B | |
| SCHEMBL5404702 | 0.70 | PDE4B (0.51) | MAPTPDE4BTERTL3MBTL1 | |
| SCHEMBL9593574 | 0.69 | TOP2A (0.53) | TP53MAPTHPGDTERT | |
| SCHEMBL9595513 | 0.69 | TOP2A (0.59) | TP53MAPTHPGDTERTL3MBTL1 | |
| SCHEMBL9593251 | 0.69 | TOP2A (0.46) | TP53MAPTHPGDTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133672-A1 | DERIVATIVES OF QUINOLINE-3-CARBOXYLIC ACID AND THEIR MEDICAL USE | CLANOTECH AB (SE) | 2010-11-25 | — | — | WO | disclosed |