Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11030238 | 0.88 | KDM4E (0.46) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL11030232 | 0.88 | KDM4E (0.46) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL1917106 | 0.87 | KDM4E (0.49) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL2466877 | 0.85 | KDM4E (0.54) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL30481035 | 0.84 | KDM4E (0.53) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL1918075 | 0.84 | KDM4E (0.53) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL1917389 | 0.83 | KDM4E (0.52) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL11030757 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL14354437 | 0.81 | KDM4E (0.51) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL1917947 | 0.81 | KDM4E (0.48) | KDM4ESMN1; SMN2L3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193120-A1 | 2-SUBSTITUTED-6-AMINO-5-ALKYL, ALKENYL OR ALKYNYL-4-PYRIMIDINECARBOXYLIC ACIDS AND 6-SUBSTITUTED-4-AMINO-3- ALKYL, ALKENYL OR ALKYNYL PICOLINIC ACIDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009046090-A1 | 2-SUBSTITUTED-6-AMINO-5-ALKYL, ALKENYL OR ALKYNYL-4-PYRIMIDINECARBOXYLIC ACIDS AND 6-SUBSTITUTED-4-AMINO-3- ALKYL, ALKENYL OR ALKYNYL PICOLINIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | WO | disclosed |