Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 3/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721132 | 0.85 | KDM4E (0.53) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL719097 | 0.85 | KDM4E (0.42) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL716661 | 0.83 | KDM4E (0.43) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL721639 | 0.83 | KDM4E (0.42) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL719560 | 0.82 | NOTUM (0.51) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1918257 | 0.81 | KDM4E (0.40) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL721162 | 0.81 | KDM4E (0.51) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL719542 | 0.80 | ERN1 (0.39) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3781927 | 0.80 | DPP4 (0.33) | KDM4EPKMRCE1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3455141 | 0.78 | HTT (0.39) | KDM4ESMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193120-A1 | 2-SUBSTITUTED-6-AMINO-5-ALKYL, ALKENYL OR ALKYNYL-4-PYRIMIDINECARBOXYLIC ACIDS AND 6-SUBSTITUTED-4-AMINO-3- ALKYL, ALKENYL OR ALKYNYL PICOLINIC ACIDS AND THEIR USE AS HERBICIDES | Dow AgroSciences LLC (US) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009046090-A1 | 2-SUBSTITUTED-6-AMINO-5-ALKYL, ALKENYL OR ALKYNYL-4-PYRIMIDINECARBOXYLIC ACIDS AND 6-SUBSTITUTED-4-AMINO-3- ALKYL, ALKENYL OR ALKYNYL PICOLINIC ACIDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-04-09 | — | — | WO | disclosed |