2-Pyrrolidone

2-Pyrrolidone

SCHEMBL378717

C=CN1C=NCC1.O=C1CCCN1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.46
FKBP5 Q13451 1/20 0.40
CRBN Q96SW2 1/20 0.40
KDM4E B2RXH2 2/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL168330 0.76
Iodide SCHEMBL11329545 0.74
SCHEMBL5090572 0.74
2-Pyrrolidone SCHEMBL28284820 0.73 OR51E2 (0.60) OR51E2FKBP5CRBNKDM4EGAA
2-Pyrrolidone SCHEMBL28605350 0.70 OR51E2 (0.46) OR51E2FKBP5CRBNKDM4EGAA
2-Pyrrolidone SCHEMBL3695275 0.69 OR51E2 (0.65) OR51E2FKBP5CRBNKDM4EGAA
2-Pyrrolidone SCHEMBL6535468 0.68
2-Pyrrolidone SCHEMBL2143364 0.68
2-Pyrrolidone SCHEMBL2702899 0.68
2-Pyrrolidone SCHEMBL622496 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470656-B2 Pre-moistened wipes THE PROCTER & GAMBLE COMPANY (US) 2008-12-30 US claimed
EP-1290121-B1 HARD SURFACE CLEANING COMPOSITIONS PROCTER & GAMBLE (US) 2008-10-29 EP claimed
US-20050153857-A1 Hard surface cleaning compositions, premoistened wipes, methods of use, and articles comprising said compositions or wipes and instructions for use resulting in easier cleaning and maintenance, improved surface appearance and/or hygiene under stress conditions such as no-rinse SHERRY ALAN E (US) 2005-07-14 US claimed
US-6716805-B1 HARD SURFACE CLEANING COMPOSITIONS, PREMOISTENED WIPES, METHODS OF USE, AND ARTICLES COMPRISING SAID COMPOSITIONS OR WIPES AND INSTRUCTIONS FOR USE RESULTING IN EASIER CLEANING AND MAINTENANCE, IMPROVED SURFACE APPEARANCE AND/OR HYGIENE UNDER STRESS CONDITIONS SUCH AS NO-RINSE THE PROCTER & GAMBLE COMPANY 2004-04-06 US claimed
US-8632793-B2 Top-biased beneficial components on substrates THE PROCTER & GAMBLE COMPANY (US) 2014-01-21 US disclosed
EP-1404278-B1 HIGH AMOUNT OF BENEFICIAL COMPONENTS IN THE TOP OF A SUBSTRATE PROCTER & GAMBLE (US) 2012-01-25 EP disclosed
EP-2036481-A2 Hard surface cleaning compositions, premoistened wipes, methods of use, and articles comprising said compositions or wipes and instructions for use resulting in easier cleaning and maintenance, improved surface appearance and/or hygiene under stress conditions such as no-rinse The Procter and Gamble Company (US) 2009-03-18 EP disclosed
US-7470656-B2 Pre-moistened wipes THE PROCTER & GAMBLE COMPANY (US) 2008-12-30 US disclosed
EP-1290121-B1 HARD SURFACE CLEANING COMPOSITIONS PROCTER & GAMBLE (US) 2008-10-29 EP disclosed
US-20070116748-A1 Top-biased beneficial components on substrates ISELE OLAF 2007-05-24 US disclosed
US-7166292-B2 Top-biased beneficial components on substrates THE PROCTER & GAMBLE COMPANY (US) 2007-01-23 US disclosed
EP-1661503-A2 Hard surface cleaning compositions, premoistened wipes, methods of use, and articles comprising said compositions The Procter and Gamble Company (US) 2006-05-31 EP disclosed
US-20020175092-A1 Method of cleaning floors and other large surfaces STULENS MARIELLE JEANNINE COLE (BE) 2002-11-28 US disclosed
EP-1255521-A1 DISPOSABLE ARTICLE COMPRISING AN APERTURED LAMINATE WEB THE PROCTER & GAMBLE COMPANY (US) 2002-11-13 EP disclosed
EP-1242022-A1 DISPOSABLE ARTICLE COMPRISING AN APERTURED LAMINATE WEB THE PROCTER & GAMBLE COMPANY (US) 2002-09-25 EP disclosed
EP-1215987-A1 A METHOD OF CLEANING FLOORS AND OTHER LARGE SURFACES THE PROCTER & GAMBLE COMPANY (US) 2002-06-26 EP disclosed
WO-2001045615-A1 DISPOSABLE ARTICLE COMPRISING AN APERTURED LAMINATE WEB THE PROCTER & GAMBLE COMPANY (US) 2001-06-28 WO disclosed
WO-2001045613-A1 DISPOSABLE ARTICLE COMPRISING AN APERTURED LAMINATE WEB THE PROCTER & GAMBLE COMPANY (US) 2001-06-28 WO disclosed
WO-2001022860-A1 A METHOD OF CLEANING FLOORS AND OTHER LARGE SURFACES THE PROCTER & GAMBLE COMPANY (US) 2001-04-05 WO disclosed
EP-1086648-A1 A method of cleaning floors and other large surfaces The Procter & Gamble Company (US) 2001-03-28 EP disclosed