Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL766641 | 1.00 | TRPV1 (0.80) | TRPV1KCNH2 | |
| SCHEMBL766640 | 1.00 | TRPV1 (0.80) | TRPV1KCNH2 | |
| SCHEMBL13257578 | 0.90 | TRPV1 (0.79) | TRPV1KCNH2 | |
| SCHEMBL766808 | 0.90 | TRPV1 (0.79) | TRPV1KCNH2 | |
| SCHEMBL766809 | 0.90 | TRPV1 (0.79) | TRPV1KCNH2 | |
| SCHEMBL766751 | 0.89 | TRPV1 (1.00) | TRPV1KCNH2 | |
| SCHEMBL766715 | 0.89 | TRPV1 (1.00) | TRPV1KCNH2 | |
| SCHEMBL766716 | 0.89 | TRPV1 (1.00) | TRPV1KCNH2 | |
| SCHEMBL766720 | 0.87 | TRPV1 (0.79) | TRPV1KCNH2 | |
| SCHEMBL766497 | 0.87 | TRPV1 (0.79) | TRPV1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393789-A1 | ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES | N.V. Organon (NL) | 2011-12-14 | — | — | EP | disclosed |
| WO-2010091009-A1 | ISOXAZOLE-3-CARBOXAMIDE DERIVATIVES | N.V. ORGANON (NL) | 2010-08-12 | — | — | WO | disclosed |