Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19133987 | 1.00 | MAPT (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL479283 | 0.92 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2569908 | 0.92 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL480808 | 0.90 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL5318399 | 0.90 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2569773 | 0.90 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL31093973 | 0.90 | RXFP1 (0.42) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2570768 | 0.89 | RXFP1 (0.41) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2570765 | 0.89 | RXFP1 (0.41) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2572053 | 0.89 | RXFP1 (0.41) | MAPTRXFP1SMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |