Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3788180 | 1.00 | CA1 (0.67) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL28522866 | 0.92 | CA1 (0.67) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL28407606 | 0.92 | CA1 (0.75) | CA1CA4FFAR3LCKFYN | |
| Acetic Acid SCHEMBL8853012 | 0.91 | CA1 (0.80) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL28566225 | 0.88 | CA1 (0.69) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL29238271 | 0.88 | CA1 (0.69) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL28922743 | 0.88 | CA1 (0.69) | CA1CA4FFAR3LCKFYN | |
| Oxalic Acid SCHEMBL27984847 | 0.88 | CA1 (0.69) | CA1CA4FFAR3LCKFYN | |
| Acetic Acid SCHEMBL11410545 | 0.87 | CA1 (0.73) | CA1CA4FFAR3LCKFYN | |
| Acetic Acid SCHEMBL8160470 | 0.87 | CA1 (0.73) | CA1CA4FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100034730-A1 | One-step, paste-state mechanochemical process for the synthesis of zinc oxide nanoparticles | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (HK) | 2010-02-11 | — | — | US | disclosed |