SCHEMBL378849

SCHEMBL378849

C=C(C)C(=O)Oc1ccc(-c2cc(OC(=O)C(=C)C)cc(OC(=O)C(=C)C)c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.54
KMT2A Q03164 3/20 0.50
ATM Q13315 1/20 0.50
HSD17B10 Q99714 1/20 0.43
RXRA P19793 1/20 0.42
MAPT P10636 4/20 0.41
LMNA P02545 3/20 0.41
TP53 P04637 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
TTR P02766 1/20 0.41
CYP3A4 P08684 1/20 0.41
GAA P10253 1/20 0.41
ABL1 P00519 2/20 0.39
ABCB1 P08183 2/20 0.39
BCR P11274 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
BACE1 P56817 2/20 0.37
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24440807 1.00 ELANE (0.54) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL17081087 0.96 ELANE (0.54) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL15339076 0.96 ELANE (0.49) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL15339043 0.96 ELANE (0.49) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL17081094 0.93 ELANE (0.57) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL15624648 0.91 ELANE (0.47) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL15626982 0.91 ELANE (0.47) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL20174178 0.91 ELANE (0.47) ELANEKMT2AATMHSD17B10RXRA
SCHEMBL15330105 0.91 ELANE (0.49) ELANEKMT2AATMRXRAMAPT
SCHEMBL803168 0.91 ELANE (0.62) ELANEKMT2AATMHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4056667-B1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-08-02 EP disclosed
US-20230183571-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-06-15 US disclosed
US-20230183571-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-06-15 US disclosed
EP-4194529-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS Merck Patent GmbH (DE) 2023-06-14 EP disclosed
WO-2023066953-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2023-04-27 WO disclosed
WO-2022101151-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS MERCK PATENT GMBH (DE) 2022-05-19 WO disclosed
US-11091699-B2 Liquid crystal composition and liquid crystal display element Shijiazhuang Chengzhi Yonghua Display Material Co., Ltd (CN) 2021-08-17 US disclosed
US-11078420-B2 Liquid crystal composition and liquid crystal display element SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2021-08-03 US disclosed
EP-3816264-A1 LIQUID CRYSTAL MEDIA COMPRISING POLYMERISABLE COMPOUNDS Merck Patent GmbH (DE) 2021-05-05 EP disclosed
EP-2906662-B1 EMITTER AND HOSTS WITH AROMATIC UNITS MERCK PATENT GMBH (DE) 2020-04-01 EP disclosed
US-8313669-B2 Liquid-crystal display MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-11-20 US disclosed
US-8313669-B2 Liquid-crystal display MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 2012-11-20 US disclosed
EP-2181174-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2012-01-25 EP disclosed
EP-2181174-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2012-01-25 EP disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2011-05-05 US disclosed
EP-2181174-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2010-05-05 EP disclosed
WO-2009030322-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed
WO-2009030322-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2009-03-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110101269-A1 LIQUID-CRYSTAL DISPLAY KLK3, LPXN, PSAP ELANE 1234/4885KMT2A 2905/4885ATM 2017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.