Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044370 | 0.89 | HRH1 (0.40) | DRD2DRD3HRH1 | |
| Hydrochloric Acid SCHEMBL3039117 | 0.87 | KCNH2 (0.37) | KCNH2KCNJ1DRD2HTR1AHTR2A | |
| SCHEMBL3046173 | 0.87 | HRH1 (0.41) | DRD2DRD3HRH1 | |
| Hydrochloric Acid SCHEMBL3040610 | 0.86 | HRH1 (0.40) | DRD2DRD3HRH1 | |
| SCHEMBL3049190 | 0.86 | HRH1 (0.41) | KCNH2DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL3040347 | 0.85 | DRD3 (0.36) | KCNH2DRD2HTR2ADRD3HRH1 | |
| SCHEMBL3047749 | 0.84 | HRH1 (0.41) | KCNH2DRD2HTR2ADRD3HRH1 | |
| SCHEMBL3047419 | 0.84 | CHRM5 (0.40) | KCNH2DRD2HTR2ADRD3MAPT | |
| Hydrochloric Acid SCHEMBL3040320 | 0.83 | HRH1 (0.40) | KCNH2DRD2HTR2ADRD3HRH1 | |
| SCHEMBL3044716 | 0.83 | TP53 (0.36) | KCNH2DRD2HTR2ADRD3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377967-B2 | Piperidine derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2013-02-19 | — | — | US | disclosed |
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331365-A1 | PIPERIDINE DERIVATIVE | HRH4, HRH3, HRH2 | KCNH2 528/4885KCNJ1 605/4885DRD2 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.