Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135988 | 1.00 | PRCP (0.47) | PRCPTLR2DPP7ALDH1A1ATM | |
| SCHEMBL5280177 | 0.92 | PRCP (0.43) | PRCPTLR2DPP7ALDH1A1ATM | |
| SCHEMBL8257937 | 0.88 | PRCP (0.51) | PRCPTLR2DPP7ALDH1A1ATM | |
| SCHEMBL2638667 | 0.88 | PRCP (0.51) | PRCPTLR2DPP7ALDH1A1ATM | |
| SCHEMBL2713588 | 0.88 | PRCP (0.51) | PRCPTLR2DPP7ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL7370055 | 0.86 | PRCP (0.50) | PRCPTLR2DPP7ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL7366846 | 0.86 | PRCP (0.50) | PRCPTLR2DPP7ALDH1A1ATM | |
| SCHEMBL25413989 | 0.84 | SOAT1 (0.45) | PRCPTLR2DPP7ALDH1A1DPP4 | |
| SCHEMBL16774368 | 0.84 | SOAT1 (0.45) | PRCPTLR2DPP7ALDH1A1DPP4 | |
| SCHEMBL629326 | 0.83 | PRCP (0.54) | PRCPTLR2DPP7NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265448-A1 | RILUZOLE PRODRUGS AND THEIR USE | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2018-01-10 | — | — | EP | disclosed |
| WO-2016140879-A9 | RILUZOLE PRODRUGS AND THEIR USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016140878-A9 | PRODRUGS RILUZOLE AND THEIR METHOD OF USE | BIOHAVEN PHARMACEUTICAL HOLDING COMPANY LTD. (US) | 2016-10-20 | — | — | WO | disclosed |
| CN-104844687-A | Alkylamine-substituted dicyanopyridine and amino acid ester prodrugs thereof | BAYER IP GMBH | 2015-08-19 | — | — | CN | disclosed |
| EP-2640719-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2013-09-25 | — | — | EP | disclosed |
| WO-2012068234-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-05-24 | — | — | WO | disclosed |
| EP-2398474-A1 | INHIBITORS OF HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096777-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | WO | disclosed |
| WO-2007084314-A2 | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | INCYTE CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
| EP-0873519-A4 | HIV PROTEASE INHIBITORS | SCRIPPS RESEARCH INST (US) | 2005-04-27 | — | — | EP | disclosed |
| WO-2000001714-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-01-13 | — | — | WO | disclosed |
| EP-0873519-A1 | HIV PROTEASE INHIBITORS | The Scripps Research Institute (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1997021100-A9 | HIV PROTEASE INHIBITORS | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997021100-A1 | HIV PROTEASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1997-06-12 | — | — | WO | disclosed |
| US-4965283-A | Anticonvillsants, antiepileptic agents | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1990-10-23 | — | — | US | disclosed |
| US-3971737-A | [2-Methyl-Ala6 ]LRH | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-07-27 | — | — | US | disclosed |
| US-3947575-A | Peptides as argiotensin converting enzyme inhibitors | E. R. SQUIBB & SONS, INC. (US) | 1976-03-30 | — | — | US | disclosed |