Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 7/20 | 0.48 |
| ▸ | F2 | P00734 | 5/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.48 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3794040 | 0.86 | ST14 (0.61) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL851641 | 0.85 | ST14 (0.47) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL851322 | 0.84 | ST14 (0.46) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL851337 | 0.83 | NPC1 (0.71) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL3790621 | 0.83 | ST14 (0.47) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL3788711 | 0.83 | ST14 (0.70) | NPC1ST14F2PRSS1PRSS2 | |
| SCHEMBL851551 | 0.82 | ST14 (0.69) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL851898 | 0.82 | NPC1 (0.54) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL850974 | 0.81 | ST14 (0.69) | NPC1RAB9ASCN9AST14F2 | |
| SCHEMBL3795204 | 0.80 | ST14 (0.47) | NPC1RAB9ASCN9AST14F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010133748-A1 | PROTEASE INHIBITORS | ORION CORPORATION (FI) | 2010-11-25 | — | — | WO | disclosed |