Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 19/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.75 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.75 |
| ▸ | GSK3A | P49840 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL497447 | 0.93 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497175 | 0.93 | GSK3B (0.75) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8273486 | 0.92 | GSK3B (0.76) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8272164 | 0.92 | GSK3B (0.73) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL8272178 | 0.90 | GSK3B (0.69) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL10106769 | 0.90 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL497651 | 0.90 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL10106922 | 0.90 | GSK3B (0.71) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL10106965 | 0.90 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL10106916 | 0.90 | GSK3B (0.70) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2266979-A1 | 2-morpholino-4-pyrimidone compounds | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |
| EP-2258701-A1 | 2-morpholino-4-pyrimidone compound | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-12-08 | — | — | EP | disclosed |