SCHEMBL3791019

SCHEMBL3791019

Cc1ccccc1[Sn](Cl)(Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ACHE P22303 3/20 0.47
ALDH1A1 P00352 4/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
ESR1 P03372 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030738 0.83 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL29463897 0.83 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL1029603 0.83 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL10937451 0.77 TSHR (0.41) TSHRACHEALDH1A1CA1CA2
SCHEMBL1031960 0.77 TSHR (0.53) TSHRACHEALDH1A1CA1CA2
SCHEMBL5953407 0.74 TSHR (0.50) TSHRACHEALDH1A1CA1CA2
SCHEMBL1538839 0.72 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL1032375 0.72 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL1405710 0.72 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL1538712 0.72 TSHR (0.47) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0761733-B1 Rubber compositions and pneumatic tires using the same BRIDGESTONE CORP (JP) 2007-05-09 EP claimed
US-8394920-B2 Composition for resin and optical lens obtained therefrom MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-03-12 US disclosed
CN-101932630-B Composition for resin and optical lens obtained therefrom MITSUBISHI GAS CHEMICAL CO 2012-12-05 CN disclosed
CN-101463133-B Manufacturing method and apparatus of optical material SEIKO EPSON CORP 2011-03-02 CN disclosed
CN-101175792-B Curable composition MITSUBISHI GAS CHEMICAL CO 2011-01-26 CN disclosed
US-20100331515-A1 COMPOSITION FOR RESIN AND OPTICAL LENS OBTAINED THEREFROM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2010-12-30 US disclosed
CN-101932630-A Composition for resin and optical lens obtained therefrom MITSUBISHI GAS CHEMICAL CO 2010-12-29 CN disclosed
EP-2243798-A1 COMPOSITION FOR RESIN AND OPTICAL LENS OBTAINED THEREFROM Mitsubishi Gas Chemical Company, Inc. (JP) 2010-10-27 EP disclosed
CN-101463133-A Manufacturing method and apparatus of optical material SEIKO EPSON CORP (JP) 2009-06-24 CN disclosed
CN-101175792-A curable composition MITSUBISHI GAS CHEMICAL CO (JP) 2008-05-07 CN disclosed
EP-0761733-B1 Rubber compositions and pneumatic tires using the same BRIDGESTONE CORP (JP) 2007-05-09 EP disclosed
WO-2007022945-A2 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS VIACATT N.V. (BE) 2007-03-01 WO disclosed
CN-1105125-C Rubber suitable for tire tread TAIWAN RUBBER CO LTD (CN) 2003-04-09 CN disclosed
US-6133376-A HIGH PERFORMANCE TIRE TREAD INCLUDES: PREFERRED PERCENTAGE OF LOW MOLECULAR WEIGHT COUPLED COPOLYMER OF AROMARTIC VINYL AND CONJUGATED DIENE, A MIDDLE MOLECULAR WEIGHT UNCOUPLED COPOLYMER AND A HIGH MOLECULAR WEIGHT COPULED COPOLYMER TAIWAN SYNTHETIC RUBBER CO. (TW) 2000-10-17 US disclosed
CN-1222529-A Rubber suitable for tire tread TAIWAN SYNTHETIC RUBBER CO LTD (CN) 1999-07-14 CN disclosed
US-5726237-A COMPOSITION OF A RUBBER AND CARBON BLACK HAVING LOW ROLLING RESISTANCE AND WET SKID RESISTANCE BRIDGESTONE CORPORATION (JP) 1998-03-10 US disclosed
EP-0761733-A2 Rubber compositions and pneumatic tires using the same Bridgestone Corporation (JP) 1997-03-12 EP disclosed
US-4093636-A IN PRESENCE OF ORGANIC HYDROPEROXIDES AND A TIN CATALYST RHONE - POULENC INDUSTRIES (FR) 1978-06-06 US disclosed
US-3956532-A Recovery of metal halides OWENS-ILLINOIS, INC. (US) 1976-05-11 US disclosed