Diphenylamine

Diphenylamine

SCHEMBL3791309

O=C1NC(=O)C2CC=CCC12.c1ccc(Nc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.50
TP53 P04637 1/20 0.46
HSD17B10 Q99714 4/20 0.44
ALDH1A1 P00352 7/20 0.43
MAPK1 P28482 2/20 0.43
ALOX15 P16050 2/20 0.43
ALOX12 P18054 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
TSHR P16473 2/20 0.43
PTGS1 P23219 1/20 0.43
SLC6A2 P23975 1/20 0.43
PTGS2 P35354 1/20 0.43
HTR2B P41595 1/20 0.43
MEN1 O00255 5/20 0.41
MAPT P10636 5/20 0.41
KMT2A Q03164 5/20 0.41
CYP3A4 P08684 3/20 0.41
GSK3B P49841 2/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16123845 0.79 PDE4A (0.38) TDP1TP53HSD17B10ALDH1A1MAPK1
SCHEMBL1568503 0.79 PDE4A (0.38) TDP1TP53HSD17B10ALDH1A1MAPK1
SCHEMBL9632348 0.79 PDE4A (0.38) TDP1TP53HSD17B10ALDH1A1MAPK1
SCHEMBL1568506 0.79 PDE4A (0.38) TDP1TP53HSD17B10ALDH1A1MAPK1
SCHEMBL2547401 0.79 PDE4A (0.38) TDP1TP53HSD17B10ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL5271499 0.77 PDE4A (0.37) TDP1TP53HSD17B10ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL10577443 0.75 PDE4A (0.36) TDP1TP53HSD17B10ALDH1A1MAPK1
SCHEMBL9500672 0.70 PARP1 (0.37) TP53HSD17B10ALDH1A1MAPK1ALOX15
Phosphoric Acid SCHEMBL5326568 0.70 PDE4A (0.33) TP53HSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL17432744 0.67 BRD4 (0.41) TSHRCRBNCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207868-A1 TRACTOR HYDRAULIC FLUID COMPOSITIONS AND PREPARATION THEREOF Chevron U.S.A., Inc. (US) 2010-07-21 EP claimed
WO-2009042396-A1 TRACTOR HYDRAULIC FLUID COMPOSITIONS AND PREPARATION THEREOF CHEVRON U.S.A. INC. (US) 2009-04-02 WO claimed
WO-2009032403-A1 HYDRAULIC FLUID COMPOSITIONS AND PREPARATION THEREOF CHEVRON U.S.A. INC. (US) 2009-03-12 WO claimed