Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL620001 | 1.00 | KMT2A (0.41) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL622262 | 0.89 | KMT2A (0.42) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL621992 | 0.89 | KMT2A (0.42) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL621982 | 0.89 | KMT2A (0.40) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL620405 | 0.87 | HPGD (0.47) | KMT2AHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL622117 | 0.86 | HPGD (0.48) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL622667 | 0.84 | HPGD (0.44) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL622660 | 0.82 | HPGD (0.47) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL619404 | 0.82 | HPGD (0.47) | KMT2AHPGDNPC1RAB9AMAPT | |
| SCHEMBL619652 | 0.81 | HPGD (0.44) | KMT2AHPGDNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084152-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2010-07-29 | — | — | WO | disclosed |