SCHEMBL379250

SCHEMBL379250

O=C(O)NC1CCNCC1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.70
POLB P06746 1/20 0.61
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
TSHR P16473 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
PMP22 Q01453 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL15546957 0.98 EPHX1 (0.67) EPHX1POLBGABRPGABRDGABRA1
Bicarbonate SCHEMBL28207579 0.91 EPHX1 (0.59) EPHX1POLBGABRPGABRDGABRA1
SCHEMBL2324691 0.91 EPHX1 (0.62) EPHX1POLBGABRPGABRDGABRA1
SCHEMBL3614519 0.91 EPHX1 (0.62) EPHX1POLBGABRPGABRDGABRA1
SCHEMBL22233774 0.91 EPHX1 (0.62) EPHX1POLBGABRPGABRDGABRA1
Hydrochloric Acid SCHEMBL14688322 0.89 EPHX1 (0.60) EPHX1POLBGABRPGABRDGABRA1
SCHEMBL28797537 0.87 EPHX1 (0.54) EPHX1POLBGABRPGABRDGABRA1
Cyclohexanol SCHEMBL9330386 0.86 EPHX1 (0.61) EPHX1POLBGABRPGABRDGABRA1
SCHEMBL1749149 0.86
SCHEMBL512691 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 575 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102224153-B Substituted imidazo [1,2-B ] pyridazine compounds as TRK kinase inhibitors ARRAY BIOPHARMA INC 2014-04-30 CN claimed
EP-1102789-A1 MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM Menarini Ricerche S.p.A. (IT) 2001-05-30 EP claimed
WO-2000008046-A1 MONOCYCLIC COMPOUNDS HAVING NK-2 ANTAGONIST ACTION AND COMPOSITIONS CONTAINING THEM MENARINI RICERCHE S.P.A. (IT) 2000-02-17 WO claimed
WO-2026103730-A1 DIAZAHETEROCYCLIC DERIVATIVE OF PYRIDOARYL GROUP HAVING KAPPA RECEPTOR ANTAGONISTIC ACTIVITY AND COMPOSITION THEREOF, AND USE 江苏恩华药业股份有限公司 2026-05-21 WO disclosed
CN-117062813-B Polycyclic compound and application thereof 四川汇宇制药股份有限公司 2026-05-19 CN disclosed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
US-12479845-B2 Imidazopyridine derivative compounds and use of same HANMI PHARM. CO., LTD. (KR) 2025-11-25 US disclosed
WO-2025233682-A1 ANTIBODY DRUG CONJUGATES COMPRISING STING AGONISTS AND USES THEREOF LIGACHEM BIOSCIENCES INC. (KR) 2025-11-13 WO disclosed
EP-4624464-A1 PYRIDINE POLYCYCLIC COMPOUND INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF Shanghai Hansoh Biomedical Co., Ltd. (CN) 2025-10-01 EP disclosed
WO-2025096710-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 WO disclosed
EP-4536656-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 Therapeutics, Inc. (US) 2025-04-16 EP disclosed
US-5246939-A Antiadrenergic systems for lower urinary apparatus SYNTHELABO (FR) 1993-09-21 US disclosed
US-5244894-A Treating disorders involving hyperactivity of the alpha 1-adrenergic system in lower urinary tract SYNTHELABO 1993-09-14 US disclosed
US-5189036-A Cardiovascular agents; class III antiarrhythmic agents SCHERING AG (DE) 1993-02-23 US disclosed
EP-0522914-A1 2-Piperidinylpyrimidin-4-carboxamide derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1993-01-13 EP disclosed
CN-1067885-A 2-aminopyrimidine-4-carboxamides derivatives and method for making and medical applications SYNTHELABO (FR) 1993-01-13 CN disclosed
EP-0520882-A1 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their application in therapy SYNTHELABO (FR) 1992-12-30 EP disclosed
EP-0520883-A1 2-Aminopyrimidin-4-carboxamide derivatives, their preparation and their use in therapy SYNTHELABO (FR) 1992-12-30 EP disclosed
EP-0467325-A2 Carbostyril derivatives SYNTEX (U.S.A.) INC. (US) 1992-01-22 EP disclosed
US-5082847-A Antiarrhythmia SYNTEX (U.S.A.) INC. (US) 1992-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12479845-B2 Imidazopyridine derivative compounds and use of same KDM1A, KDM1B, KDM2A EPHX1 1307/4885POLB 2481/4885GABRP 3333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.