Sugi Predict

Sugi Predict / Compounds / O-Xylene

O-Xylene

O-Xylene

SCHEMBL3792592

CCCCCCCCCCCCCCCl.Cc1ccccc1C.N

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 3/20 0.56
▸ ALDH1A1 P00352 3/20 0.56
▸ TP53 P04637 1/20 0.45
▸ ACHE P22303 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.42
▸ P2RX7 Q99572 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.38
▸ LMNA P02545 2/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ RAB9A P51151 2/20 0.38
▸ HTT P42858 2/20 0.38
▸ USP2 O75604 1/20 0.38
▸ ALOX15 P16050 1/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ HSP90AA1 P07900 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ JAK2 O60674 1/20 0.38
▸ PAX8 Q06710 1/20 0.38
▸ LTA4H P09960 2/20 0.37
▸ LIPG Q9Y5X9 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL11314983 1.00 TSHR (0.56) TSHRALDH1A1TP53ACHETDP1
O-Xylene SCHEMBL28713896 0.96 TSHR (0.55) TSHRALDH1A1TP53ACHETDP1
Tridecane SCHEMBL27654408 0.89 TSHR (0.56) TSHRALDH1A1TP53ACHEP2RX7
O-Xylene SCHEMBL27656778 0.86 TSHR (0.53) TSHRALDH1A1TP53ACHETDP1
Octane SCHEMBL8046192 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7
O-Xylene SCHEMBL10941793 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7
Hexadecane SCHEMBL9547561 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7
Nonane SCHEMBL10943433 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7
Decane SCHEMBL9863298 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7
Dodecane SCHEMBL28874984 0.86 TSHR (0.59) TSHRALDH1A1TP53ACHEP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100197809-A1 SKIN SOLUTION AND PREPARATION METHOD THEREOF ORTIZ ALVARO ERNESTO 2010-08-05 — — US claimed
US-20100197809-A1 SKIN SOLUTION AND PREPARATION METHOD THEREOF ORTIZ ALVARO ERNESTO 2010-08-05 — — US disclosed
WO-2009148417-A1 METHOD OF TREATMENT ALPHAMED PHARMACEUTICALS CORP. (US) 2009-12-10 — — WO disclosed
US-20080234225-A1 Method of treatment LEZDEY JOHN 2008-09-25 — — US disclosed
EP-0369992-B1 Toilet bowl cleaner KIWI BRANDS INC (US) 1995-01-18 — — EP disclosed
EP-0423392-B1 Toilet bowl cleaner KIWI BRANDS INC (US) 1995-01-18 — — EP disclosed
US-5346886-A FOR INCREASING CHEMICAL STABILITY AND PENETRATION OF PROTEASE INHIBITOR IN THE SKIN LEZDEY, JARETT 1994-09-13 — — US disclosed
EP-0423392-A1 Toilet bowl cleaner KIWI BRANDS INC (US) 1991-04-24 — — EP disclosed
EP-0250268-B1 TOILET BOWL CLEANER KIWI BRANDS INC (US) 1990-12-05 — — EP disclosed
EP-0369992-A2 Toilet bowl cleaner KIWI BRANDS INC (US) 1990-05-23 — — EP disclosed
US-4911858-A Mixture of polyoxyalkylene oxide, guar gum and inert salt KIWI BRANDS, INC. (US) 1990-03-27 — — US disclosed
US-4780236-A Lavoratory cleansing block containing polyethylene gycol disteatrate, guar gum and sodium chloride KIWI BRANDS, INC. (US) 1988-10-25 — — US disclosed
US-4722801-A LONG LASTING KIWI BRANDS, INC. (US) 1988-02-02 — — US disclosed
EP-0250268-A1 Toilet bowl cleaner KIWI BRANDS INC (US) 1987-12-23 — — EP disclosed
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