Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | USP2 | O75604 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.63 |
| ▸ | NT5E | P21589 | 2/20 | 0.63 |
| ▸ | TOP2A | P11388 | 2/20 | 0.63 |
| ▸ | RELA | Q04206 | 1/20 | 0.63 |
| ▸ | RORC | P51449 | 8/20 | 0.60 |
| ▸ | ALB | P02768 | 3/20 | 0.60 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | GLI1 | P08151 | 1/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.60 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.60 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.60 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.56 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.56 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112694 | 1.00 | PTPN1 (0.63) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL6112674 | 0.91 | PTPN1 (0.51) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL6112660 | 0.90 | CA9 (0.62) | PTPN1NT5EPTGES | |
| SCHEMBL3796643 | 0.80 | PTPN1 (0.61) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL10214423 | 0.79 | PTPN1 (0.86) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL14344982 | 0.79 | PTPN1 (0.86) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL14666403 | 0.79 | PTPN1 (0.86) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL13855646 | 0.79 | PTPN1 (0.86) | PTPN1USP2LMNAHIF1ANT5E | |
| Betulin SCHEMBL4430413 | 0.79 | PTPN1 (0.92) | PTPN1USP2LMNAHIF1ANT5E | |
| Betulin SCHEMBL7749571 | 0.78 | PTPN1 (1.00) | PTPN1USP2LMNAHIF1ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134830-A1 | TRITERPENOID DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | UNIVERSIDADE DE COIMBRA (PT) | 2010-11-25 | — | — | WO | disclosed |