Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15841657 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL15841459 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL5308623 | 0.86 | PDE4A (0.50) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL22123640 | 0.86 | PDE4A (0.50) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL9312513 | 0.86 | PDE4A (0.50) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL14556019 | 0.86 | PDE4A (0.50) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL4377760 | 0.86 | PDE4A (0.50) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL2933990 | 0.85 | PDE4A (0.54) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL15049970 | 0.83 | PDE4A (0.52) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 | |
| SCHEMBL8680823 | 0.83 | PDE4A (0.52) | SLC1A3SLC1A2SLC1A1PDE4AOR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2263423-A | — | — | None | — | — | JP | disclosed |
| EP-2193128-B1 | METHOD FOR MANUFACTURING 4-AMINOBUT-2-ENOLIDS | BAYER IP GMBH (DE) | 2016-10-26 | — | — | EP | disclosed |
| EP-2516421-B1 | New method of producing 4-aminobut-2-enolides starting from 4-alkoxyfuran-2(5H)-one or 4-arylalkoxyfuran-2-(5H)-one | BAYER IP GMBH (DE) | 2016-08-10 | — | — | EP | disclosed |
| EP-2203410-B1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2253610-B1 | Method for manufacturing of enaminocarbonyl-compounds and their use in preparing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| EP-2408764-B1 | New method for producing enaminocarbonyl compounds | BAYER CROPSCIENCE AG (DE) | 2013-07-17 | — | — | EP | disclosed |
| EP-2467374-B1 | New method for manufacturing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-05-01 | — | — | EP | disclosed |
| EP-2408765-B1 | NOVEL METHOD FOR PRODUCING ENAMINOCARBONYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2013-01-23 | — | — | EP | disclosed |
| EP-2516421-A1 | NOVEL METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES STARTING FROM 4-ALKOXYFURAN-2(5H)-ON OR 4-ARYLALKOXYFURAN-2-(5H)-ON | Bayer Intellectual Property GmbH (DE) | 2012-10-31 | — | — | EP | disclosed |
| EP-2467374-A1 | NOVEL METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2012-06-27 | — | — | EP | disclosed |
| EP-2203410-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| EP-2193128-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2010-06-09 | — | — | EP | disclosed |
| EP-2042496-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2009-04-01 | — | — | EP | disclosed |
| WO-2009036899-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| WO-2009036898-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| EP-2039678-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2009-03-25 | — | — | EP | disclosed |
| EP-0247320-B1 | 5-ARYLALKYL-4-ALKOXY-2(5H)-FURANONES, INTERMEDIATES AND PROCESS FOR THEIR PREPARATION AS WELL AS THEIR APPLICATION AS THERAPEUTICALLY ACTIVE INGREDIENTS | SCHWABE WILLMAR GMBH & CO (DE) | 1990-12-27 | — | — | EP | disclosed |
| JP-H02263423-A | ELECTROLYTE FOR ELECTROLYTIC CAPACITOR DRIVE USE | MATSUSHITA ELECTRIC IND CO LTD | 1990-10-26 | — | — | JP | disclosed |
| US-4766213-A | 1,4-dihydropyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-08-23 | — | — | US | disclosed |
| EP-0247320-A2 | 5-Arylalkyl-4-alkoxy-2(5H)-furanones, intermediates and process for their preparation as well as their application as therapeutically active ingredients | Dr. Willmar Schwabe GmbH & Co. (DE) | 1987-12-02 | — | — | EP | disclosed |