Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butane SCHEMBL9850652 | 0.88 | CYP3A4 (0.36) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL1360180 | 0.75 | TDP1 (0.50) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL30827528 | 0.73 | CYP3A4 (0.75) | TDP1CYP3A4TSHRESR1ESR2 | |
| Ethane SCHEMBL10983356 | 0.69 | TDP1 (0.43) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL246946 | 0.65 | — | — | |
| SCHEMBL2939094 | 0.65 | TDP1 (0.53) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL230096 | 0.65 | TDP1 (0.53) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL1951204 | 0.65 | TDP1 (0.86) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL9420677 | 0.65 | TDP1 (0.86) | TDP1CYP3A4TSHRESR1ESR2 | |
| SCHEMBL11664569 | 0.65 | TDP1 (0.53) | TDP1CYP3A4TSHRESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484503-B | Mikanolide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2022-05-27 | — | — | CN | claimed |
| CN-111484503-A | Mikanolide derivative and preparation method and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2020-08-04 | — | — | CN | claimed |
| CN-111039989-A | Preparation method of bis (diphenylphosphino) -palladium dichloride chiral catalyst | 西安凯立新材料股份有限公司 | 2020-04-21 | — | — | CN | claimed |
| WO-2014158647-A1 | PREPARATION OF TRIARYL RHAMNOSE CARBAMATES | DOW AGROSCIENCES LLC (US) | 2014-10-02 | — | — | WO | claimed |
| US-20140275504-A1 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES | DOW AGROSCIENCES LLC (US) | 2014-09-18 | — | — | US | claimed |
| EP-4570805-A1 | TRICYCLIC COMPOUNDS AND MEDICAL USE THEREOF | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2025-06-18 | — | — | EP | disclosed |
| WO-2025037034-A1 | THIENOTHIADIAZINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2025-02-20 | — | — | WO | disclosed |
| WO-2024217500-A1 | ISOQUINOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海赛默罗生物科技有限公司 | 2024-10-24 | — | — | WO | disclosed |
| EP-4436956-A1 | LIGANDS SPECIFICALLY TARGETING VESICULAR GLUTAMATE TRANSPORTERS FOR SUPER-RESOLUTION IMAGING | Sorbonne Université (FR) | 2024-10-02 | — | — | EP | disclosed |
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2024-07-11 | — | — | US | disclosed |
| EP-4326260-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | The Regents of The University of Michigan (US) | 2024-02-28 | — | — | EP | disclosed |
| CN-117545479-A | PI3K inhibitor, nano preparation and application thereof | 密歇根大学董事会 | 2024-02-09 | — | — | CN | disclosed |
| WO-2001077114-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-10-18 | — | — | WO | disclosed |
| US-6271234-B1 | DERIVATIVES WHICH BIND TO SEROTONERGIC RECEPTORS; TREATING DISORDERS OF THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 2001-08-07 | — | — | US | disclosed |
| EP-1000046-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2000-05-17 | — | — | EP | disclosed |
| EP-1000045-A1 | 1,4-DISUBSTITUTED PIPERAZINES | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 2000-05-17 | — | — | EP | disclosed |
| WO-1999006382-A1 | 1,4-DISUBSTITUTED PIPERAZINES | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999006383-A1 | PIPERAZINE DERIVATIVES ACTIVE ON THE LOWER URINARY TRACT | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1999-02-11 | — | — | WO | disclosed |
| EP-0489877-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES. | UPJOHN CO (US) | 1992-06-17 | — | — | EP | disclosed |
| US-4871748-A | RODENTICIDES | MAY & BAKER LIMITED (GB) | 1989-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275504-A1 | PROCESS FOR THE PREPARATION OF CERTAIN TRIARYL RHAMNOSE CARBAMATES | BCR, BCHE, C9 | TDP1 3639/4885CYP3A4 359/4885TSHR 1033/4885 |
| US-20240226104-A1 | PI3K INHIBITORS, NANOFORMULATIONS, AND USES THEREOF | PI4KA, PIK3CA, PI4KB | TDP1 3513/4885CYP3A4 3228/4885TSHR 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.