Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298472 | 0.90 | TSHR (0.34) | TSHRALDH1A1CPT1A | |
| SCHEMBL19264406 | 0.77 | TSHR (0.31) | TSHR | |
| SCHEMBL8320686 | 0.75 | CHRM2 (0.32) | — | |
| SCHEMBL19521305 | 0.74 | — | — | |
| SCHEMBL9341285 | 0.72 | CPT1A (0.35) | TSHRALDH1A1CPT1A | |
| SCHEMBL23183040 | 0.72 | TSHR (0.33) | TSHR | |
| SCHEMBL1934097 | 0.72 | — | — | |
| SCHEMBL2047860 | 0.71 | — | — | |
| SCHEMBL5034533 | 0.70 | CPT1A (0.39) | TSHRCPT1A | |
| SCHEMBL9644836 | 0.70 | TSHR (0.43) | TSHRCPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010145197-A1 | NOVEL 6-ARYLAMINO PYRIDONE SULFONAMIDES AND 6-ARYLAMINO PYRAZINONE SULFONAMDIES AS MEK INHIBITORS | CHEMIZON (BEIJING), LTD. (CN) | 2010-12-23 | — | — | WO | disclosed |