Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 16/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.43 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788978 | 0.92 | PIK3CA (0.61) | PIK3CACREBBP | |
| SCHEMBL3799035 | 0.92 | PIK3CA (0.61) | PIK3CACREBBPGPR142 | |
| SCHEMBL3796011 | 0.91 | PIK3CA (0.66) | PIK3CACREBBPGPR142 | |
| SCHEMBL3798408 | 0.91 | PIK3CA (0.62) | PIK3CACREBBP | |
| SCHEMBL2725723 | 0.90 | PIK3CA (0.50) | PIK3CACREBBPGPR142 | |
| SCHEMBL3794536 | 0.90 | PIK3CA (0.64) | PIK3CACREBBPGPR142 | |
| SCHEMBL3794123 | 0.90 | PIK3CA (0.64) | PIK3CACREBBP | |
| SCHEMBL2725831 | 0.90 | PIK3CA (0.64) | PIK3CACREBBP | |
| SCHEMBL2726054 | 0.90 | PIK3CA (0.51) | PIK3CACREBBPGPR142 | |
| SCHEMBL3795779 | 0.89 | PIK3CA (0.60) | PIK3CACREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138490-A1 | BENZOXAZEPINES AS INHIBITORS OF MTOR AND METHODS OF THEIR USE AND MANUFACTURE | EXELIXIS, INC. (US) | 2010-12-02 | — | — | WO | disclosed |