Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Silver. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000149 | 0.97 | CA4 (0.55) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Silver SCHEMBL3692335 | 0.97 | CA4 (0.48) | CA4CASP1 | |
| Potassium Ion SCHEMBL5571061 | 0.94 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Silver SCHEMBL3792176 | 0.94 | CA4 (0.46) | CA4CASP1 | |
| SCHEMBL16150006 | 0.94 | CA4 (0.59) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Potassium Ion SCHEMBL18804464 | 0.94 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| SCHEMBL3818098 | 0.94 | CA4 (0.52) | CA4CASP1FFAR3HDAC3HDAC1 | |
| Silver SCHEMBL8954105 | 0.92 | CA4 (0.44) | CA4 | |
| SCHEMBL11350148 | 0.92 | CA4 (0.48) | CA4CASP1 | |
| Potassium Ion SCHEMBL17770566 | 0.92 | CA4 (0.48) | CA4CASP1FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118329862-B | Method for detecting drug concentration based on surface-enhanced Raman spectroscopy technology | 上海默乐光检科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118329862-A | Method for detecting drug concentration based on surface-enhanced Raman spectroscopy technology | 上海默乐光检科技有限公司 | 2024-07-12 | — | — | CN | claimed |
| CN-118010703-A | Surface enhanced Raman spectrum analysis method | 上海交通大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118329862-B | Method for detecting drug concentration based on surface-enhanced Raman spectroscopy technology | 上海默乐光检科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-118329862-A | Method for detecting drug concentration based on surface-enhanced Raman spectroscopy technology | 上海默乐光检科技有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118010703-A | Surface enhanced Raman spectrum analysis method | 上海交通大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-117488409-A | Noble metal small nanoparticle superlattice film, assembly method and application thereof in SERS detection | 中国科学院合肥物质科学研究院 | 2024-02-02 | — | — | CN | disclosed |
| CN-109959646-A | A method of utilizing a variety of amino acid in silver nanoparticle bat assembling SERS substrate detection cerebral tissue | 江苏师范大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-109959646-A | A method of utilizing a variety of amino acid in silver nanoparticle bat assembling SERS substrate detection cerebral tissue | 江苏师范大学 | 2019-07-02 | — | — | CN | disclosed |
| CN-108896640-A | A kind of preparation method and application of the nano silver without enzymatic electrochemical glucose sensor | 成都师范学院 | 2018-11-27 | — | — | CN | disclosed |
| CN-108896640-A | A kind of preparation method and application of the nano silver without enzymatic electrochemical glucose sensor | 成都师范学院 | 2018-11-27 | — | — | CN | disclosed |
| EP-2007513-B1 | PREPARATION OF STABLE SILVER COLLOIDS | UNIV LINCOLN (GB) | 2010-03-24 | — | — | EP | disclosed |
| US-20090236570-A1 | PREPARATION OF STABLE SILVER COLLOIDS | THE UNIVERSITY OF LINCOLN (GB) | 2009-09-24 | — | — | US | disclosed |
| EP-2007513-A1 | PREPARATION OF STABLE SILVER COLLOIDS | The University of Lincoln (GB) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007107792-A1 | PREPARATION OF STABLE SILVER COLLOIDS | THE UNIVERSITY OF LINCOLN (GB) | 2007-09-27 | — | — | WO | disclosed |