SCHEMBL379387

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL379865	0.86	ESR1 (0.55)	TNFNOD1MAPK1PIP4K2CALDH1A1
	SCHEMBL379503	0.83	TNF (0.50)	TNFNOD1MAPK1PIP4K2CALDH1A1
	SCHEMBL380011	0.81	UTS2R (0.53)	TNFNOD1MAPK1ALDH1A1POLB
	SCHEMBL2369019	0.81	MAPK1 (1.00)	TNFNOD1MAPK1PIP4K2CALDH1A1
	SCHEMBL379504	0.81	TNF (0.47)	TNFNOD1MAPK1PIP4K2CALDH1A1
	SCHEMBL379745	0.81	EED (0.49)	TNFNOD1MAPK1ALDH1A1POLB
	SCHEMBL4946829	0.80	PDE11A (0.49)	TNFNOD1MAPK1ALDH1A1L3MBTL1
	SCHEMBL379757	0.78	CCNC (0.47)	TNFNOD1MAPK1L3MBTL1AURKB
	SCHEMBL379602	0.78	PDE11A (0.47)	TNFNOD1MAPK1ALDH1A1L3MBTL1
	SCHEMBL2900101	0.78	TNF (0.69)	TNFNOD1MAPK1PIP4K2CALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.