Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.63 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.63 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.63 |
| ▸ | ACE | P12821 | 1/20 | 0.63 |
| ▸ | HTR2A | P28223 | 1/20 | 0.63 |
| ▸ | FAP | Q12884 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3793968 | 1.00 | DPP4 (0.63) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL4535126 | 0.89 | DPP4 (0.59) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL4535123 | 0.89 | DPP4 (0.59) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL8031053 | 0.88 | DPP4 (0.52) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL29558815 | 0.88 | DPP4 (0.67) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL214373 | 0.88 | DPP4 (0.67) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL28452793 | 0.84 | DPP4 (0.63) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL15042308 | 0.84 | DPP4 (0.54) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL15043505 | 0.84 | DPP4 (0.54) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL18563379 | 0.81 | DPP4 (0.66) | DPP4DPP8DPP7DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010122578-A2 | PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES | MSN LABORATORIES LIMITED (IN) | 2010-10-28 | — | — | WO | claimed |
| WO-2010122578-A2 | PROCESS FOR THE PREPARATION OF SITAGLIPTIN AND ITS INTERMEDIATES | MSN LABORATORIES LIMITED (IN) | 2010-10-28 | — | — | WO | disclosed |