Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618209 | 0.81 | POLB (0.47) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL12871625 | 0.78 | GAA (0.53) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL3606808 | 0.77 | GAA (0.52) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL23082833 | 0.76 | POLB (0.50) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL3794031 | 0.74 | — | — | |
| SCHEMBL13160725 | 0.71 | POLB (0.53) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL13693061 | 0.69 | POLB (0.57) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL3610756 | 0.69 | POLB (0.52) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL12335143 | 0.69 | POLB (0.52) | POLBGAACYP1A2MAPTTDP1 | |
| SCHEMBL14738537 | 0.69 | POLB (0.52) | POLBGAACYP1A2MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117425-A1 | CERTAIN SUBSTITUTED PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE | BIOGEN IDEC MA INC. (US) | 2010-10-14 | — | — | WO | disclosed |