Benzoylenurea

Benzoylenurea

SCHEMBL37945

O=c1[nH]c(=O)c2ccccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 1.00
PARP1 P09874 5/20 1.00
CA12 O43570 2/20 1.00
CA9 Q16790 2/20 1.00
ALDH1A1 P00352 4/20 0.64
LMNA P02545 2/20 0.64
GPR3 P46089 2/20 0.64
HSD17B10 Q99714 2/20 0.64
CYP1A2 P05177 2/20 0.64
TNKS2 Q9H2K2 2/20 0.64
MEN1 O00255 1/20 0.64
TNKS O95271 1/20 0.64
BLM P54132 1/20 0.64
PMP22 Q01453 1/20 0.64
KMT2A Q03164 1/20 0.64
PARP15 Q460N3 1/20 0.64
GLA P06280 1/20 0.56
GAA P10253 1/20 0.56
HPGD P15428 1/20 0.56
HTT P42858 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoylenurea SCHEMBL29407209 1.00 KDM4E (1.00) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL30526893 0.98 KDM4E (0.95) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL5072763 0.98 KDM4E (0.95) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL29722891 0.98 KDM4E (0.95) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL10765540 0.96 KDM4E (0.91) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL28539125 0.90 PARP1 (0.81) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL10770094 0.90 KDM4E (0.81) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL17825209 0.90 KDM4E (0.81) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL1800055 0.88 KDM4E (0.78) KDM4EPARP1CA12CA9ALDH1A1
Benzoylenurea SCHEMBL1801421 0.87 KDM4E (0.75) KDM4EPARP1CA12CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4650 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060970-A1 Use of a Therapeutic Agent with Phosphodiesterase-7 Inhibitory Activity for the Treatment and Prevention of Diseases Associated with Chronic Fatigue, Exhaustion and/or Exertional Intolerance MITODICURE GMBH (DE) 2026-03-05 US claimed
US-20260042754-A1 Substituted Bicyclic Heteroaryl Sulfonamide Derivatives for the Treatment of Cancer NODUS ONCOLOGY LIMITED (GB) 2026-02-12 US claimed
US-20260027096-A1 PHD INHIBITORS UNIV OXFORD INNOVATION LTD (GB) 2026-01-29 US claimed
EP-4638538-A1 LIQUID RHEOLOGY CONTROL AGENT BYK-Chemie GmbH (DE) 2025-10-29 EP claimed
US-20250313535-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. 2025-10-09 US claimed
EP-4572765-A1 USE OF A THERAPEUTIC AGENT WITH PHOSPHODIESTERASE-7 INHIBITORY ACTIVITY FOR THE TREATMENT AND PREVENTION OF DISEASES ASSOCIATED WITH CHRONIC FATIGUE, EXHAUSTION AND/OR EXERTIONAL INTOLERANCE Mitodicure GmbH (DE) 2025-06-25 EP claimed
EP-4522589-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF Dice Molecules Sv, Inc. (US) 2025-03-19 EP claimed
CN-119462529-A Method for synthesizing quinazoline diketone compound 广西师范大学 2025-02-18 CN claimed
CN-118600092-A SNP locus related to rice HPPD inhibitor type resistance locus OsMRG, KASP primer group and application 江苏里下河地区农业科学研究所 2024-09-06 CN claimed
CN-112996786-B Compounds for inhibiting alpha 4 beta 7 integrin 吉利德科学公司 2024-08-20 CN claimed
US-4405623-A HYPOTENSIVE AGENTS, VASODILATORS MASAYUKI ISHIKAWA (JP) 1983-09-20 US claimed
EP-0026820-B1 METHOD OF PRODUCING RELIEF STRUCTURES RESISTANT TO A HIGH TEMPERATURE, RELIEF STRUCTURES PRODUCED THEREBY AND THEIR USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
EP-0027506-B1 PRECURSORS OF POLYIMIDES, POLYISOINDOLOQUINAZOLINE DIONES, POLYOXAZINE DIONES AND POLYQUINAZOLINE DIONES, THEIR PREPARATION AND USE SIEMENS AKTIENGESELLSCHAFT (DE) 1983-05-11 EP claimed
US-4324706-A PARTICLES OF HEAT RESISTANCT AROMATIC RESINS TEIJIN LIMITED (JP) 1982-04-13 US claimed
EP-0040793-A1 Novel quinazoline-dione compounds, process for production thereof and pharmaceutical use thereof Ishikawa, Masayuki (JP) 1981-12-02 EP claimed
EP-0035619-A1 Derivatives of 3-amino-(1H,3H)-2,4-quinazolin-diones BERRI-BALZAC Société dite: (FR) 1981-09-16 EP claimed
EP-0034258-A2 Friction material TEIJIN LIMITED (JP) 1981-08-26 EP claimed
EP-0027516-A1 Artificial pulp particles, process for producing same and paper-like sheet prepared therefrom TEIJIN LIMITED (JP) 1981-04-29 EP claimed
US-4125403-A ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, PHTHALAZINONE, AND A BENZOXAZINEDIONE OR QUINAZOLINEDIONE FUJI PHOTO FILM CO., LTD. 1978-11-14 US claimed
US-4058612-A HYPOTENSIVE AGENTS SCHERING CORPORATION (US) 1977-11-15 US claimed