SCHEMBL3796101

SCHEMBL3796101

Cc1nc(-c2ccccc2)oc1CCOc1ccc2c(c1)CCC2CC(=O)O

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.79
PPARA Q07869 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820913 1.00 PPARG (0.79) PPARGPPARA
SCHEMBL4096258 0.94 PPARG (0.81) PPARGPPARA
SCHEMBL821001 0.94 PPARG (0.81) PPARGPPARA
SCHEMBL4092451 0.91 PPARA (0.83) PPARGPPARA
SCHEMBL820990 0.91 PPARG (0.70) PPARGPPARA
SCHEMBL821461 0.90 PPARA (0.69) PPARGPPARA
SCHEMBL820931 0.89 PPARG (0.69) PPARGPPARA
SCHEMBL4682761 0.89 PPARG (1.00) PPARGPPARA
SCHEMBL6816953 0.89 PPARG (1.00) PPARGPPARA
SCHEMBL6816601 0.88 PPARG (1.00) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010141696-A1 METHODS OF TREATING OR PREVENTING PSORIASIS, AND/OR ALZHEIMER'S DISEASE USING INDANE ACETIC ACID DERIVATIVES DARA BIOSCIENCES, INC. (US) 2010-12-09 WO disclosed