Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.55 |
| ▸ | GPR142 | Q7Z601 | 10/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3754730 | 0.86 | PIK3CA (0.67) | PIK3CAGPR142CYP2D6MTORPRKDC | |
| SCHEMBL3749745 | 0.84 | PIK3CA (0.49) | PIK3CAGPR142CYP2D6MTORPRKDC | |
| SCHEMBL3762554 | 0.80 | PIK3CA (0.83) | PIK3CAGPR142MTOR | |
| SCHEMBL3758193 | 0.76 | PIK3CA (0.76) | PIK3CAMTORPRKDC | |
| SCHEMBL3757754 | 0.75 | PIK3CA (0.76) | PIK3CAGPR142MTORPRKDC | |
| SCHEMBL2726184 | 0.75 | PIK3CA (0.71) | PIK3CAGPR142 | |
| SCHEMBL3756609 | 0.74 | PIK3CA (0.71) | PIK3CAGPR142CYP2D6MTORPRKDC | |
| SCHEMBL3762270 | 0.74 | PIK3CA (0.63) | PIK3CAGPR142CYP2D6MTORPRKDC | |
| SCHEMBL2726086 | 0.74 | PIK3CA (0.46) | PIK3CAGPR142CYP2D6MTORPRKDC | |
| SCHEMBL3755382 | 0.73 | PIK3CA (0.76) | PIK3CAGPR142MTORPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118208-A1 | BENZOXAZEPIN-4- (5H) -YL DERIVATIVES AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |