SCHEMBL379627

SCHEMBL379627

OC(O)C(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853 0.75
SCHEMBL1681247 0.72
SCHEMBL5146 0.72
SCHEMBL4646874 0.71
SCHEMBL26597347 0.71
SCHEMBL27437486 0.71
SCHEMBL2508334 0.71
SCHEMBL28100275 0.71
Bromide SCHEMBL28366176 0.71
SCHEMBL25917 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250074891-A1 BIFUNCTIONAL SULPHONAMIDE COMPOUNDS Anaxis Pharma Pty Ltd (AU) 2025-03-06 US disclosed
WO-2024146559-A1 PYRIDAZINONE HETEROCYCLIC COMPOUND MYOSIN II INHIBITOR AND USE THEREOF 西藏海思科制药有限公司 2024-07-11 WO disclosed
CN-113454085-B AZA heterobicyclic inhibitors of MAT2A and methods for treating cancer 法国施维雅药厂 2024-05-07 CN disclosed
CN-117430588-A Pyridazinone heterocyclic compound Myosin II inhibitor and application thereof 西藏海思科制药有限公司 2024-01-23 CN disclosed
CN-113474347-A AZA heterobicyclic inhibitors of MAT2A and methods for treating cancer 法国施维雅药厂 2021-10-01 CN disclosed
CN-113454085-A AZA heterobicyclic inhibitors of MAT2A and methods for treating cancer 法国施维雅药厂 2021-09-28 CN disclosed
US-9845278-B2 Method for improving preservation stability of 2,2-difluoroacetaldehyde CENTRAL GLASS COMPANY, LIMITED (JP) 2017-12-19 US disclosed
US-9809534-B1 Difluoroalkylcyclopropyl amino acids and esters, and syntheses thereof ABBVIE INC. (US) 2017-11-07 US disclosed
US-9765004-B2 α,α-Difluoroacetaldehyde production method CENTRAL GLASS COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-9765004-B2 α,α-Difluoroacetaldehyde production method CENTRAL GLASS COMPANY, LIMITED (JP) 2017-09-19 US disclosed
US-20120022264-A1 METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION BAYER CROPSCIENCE AG (DE) 2012-01-26 US disclosed
EP-2408746-A1 METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION Bayer CropScience Aktiengesellschaft (DE) 2012-01-25 EP disclosed
WO-2010105747-A1 METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION BAYER CROPSCIENCE AG (DE) 2010-09-23 WO disclosed
WO-2010105747-A1 METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION BAYER CROPSCIENCE AG (DE) 2010-09-23 WO disclosed
EP-2230231-A1 Method for manufacturing 2,2-difluoroethylamine derivatives by imine hydrogenation Bayer CropScience AG (DE) 2010-09-22 EP disclosed
EP-2230231-A1 Method for manufacturing 2,2-difluoroethylamine derivatives by imine hydrogenation Bayer CropScience AG (DE) 2010-09-22 EP disclosed
US-20090185112-A1 POLARIZING PLATE PROTECTIVE FILM AND METHOD FOR MANUFACTURING THE SAME, POLARIZING PLATE AND METHOD FOR MANUFACTURING THE SAME, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2009-07-23 US disclosed
EP-0335770-B1 Novel fluorophosphonate nucleotide derivatives MERRELL PHARMA INC (US) 1997-01-15 EP disclosed
EP-0339161-A1 Novel fluorophosphonate nucleotide derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1989-11-02 EP disclosed
EP-0335770-A2 Novel fluorophosphonate nucleotide derivatives MERRELL PHARMACEUTICALS INC. (US) 1989-10-04 EP disclosed