Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17951279 | 0.84 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGPTGS1 | |
| SCHEMBL29556703 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL114826 | 0.83 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL20461926 | 0.82 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGCYP19A1 | |
| Ammonia Solution, Strong SCHEMBL28553362 | 0.82 | PIK3CD (0.51) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL789433 | 0.81 | PIK3CG (0.48) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL859011 | 0.81 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGSLC22A12 | |
| SCHEMBL17946279 | 0.80 | PIK3CD (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGCYP19A1 | |
| SCHEMBL21513479 | 0.80 | PRKDC (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGSLC22A12 | |
| SCHEMBL29661229 | 0.80 | PRKDC (0.44) | PIK3CDPIK3CAPIK3CBPIK3CGSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010135568-A1 | BENZOXAZEPINES AS INHIBITORS OF MTOR AND THEIR USE TO TREAT CANCER | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |