Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1SLC9A3
The experimentally established mechanism targets of L-Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| L-Lactic Acid SCHEMBL30139968 | 1.00 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL31634980 | 1.00 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL31634979 | 1.00 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL11059476 | 0.97 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL316634 | 0.97 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL216440 | 0.97 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL423479 | 0.97 | TP53 (0.47) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL4642218 | 0.93 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL28721225 | 0.93 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 | |
| L-Lactic Acid SCHEMBL3798027 | 0.93 | TP53 (0.44) | TP53CA1CA4CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165883-A2 | NOVEL PEPTIDE FOR SILICA SYNTHESIS AND METHOD FOR SYNTHESIZING SILICA PARTICLES USING SAME | 고려대학교 세종산학협력단 | 2020-08-20 | — | — | WO | claimed |
| US-9675962-B2 | Perovskite-type strontium titanate | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-06-13 | — | — | US | disclosed |
| US-20160346767-A1 | PEROVSKITE-TYPE STRONTIUM TITANATE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-12-01 | — | — | US | disclosed |
| CN-103906859-B | The polymer with acidic group and the preparation comprising Ti or Zr compound is comprised for passivating metallic surfaces | 巴斯夫欧洲公司 | 2016-10-12 | — | — | CN | disclosed |
| US-9434614-B2 | Perovskite-type strontium titanate | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-09-06 | — | — | US | disclosed |
| US-20150182959-A1 | RELATING TO EPOXIDATION CATALYSTS | SHELL OIL COMPANY | 2015-07-02 | — | — | US | disclosed |
| CN-103906859-A | Preparation for passivating metal surfaces, containing polymers having acid groups and containing Ti or Zr compounds | BASF SE | 2014-07-02 | — | — | CN | disclosed |
| US-20130115470-A1 | PREPARATION FOR PASSIVATING METALLIC SURFACES, COMPRISING ACID-FUNCTIONAL POLYMERS AND TI OR ZR COMPOUNDS | BASF SE (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20120189536-A1 | PEROVSKITE-TYPE STRONTIUM TITANATE | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-07-26 | — | — | US | disclosed |
| US-7662475-B2 | Alkaline-earth metal carbonate core coated with at least one group IV transition metal compound and method of making thereof | Solvay (Société Anonyme) (BE) | 2010-02-16 | — | — | US | disclosed |
| EP-1911796-A1 | Fluoropolymer composition | Solvay Solexis S.p.A. (IT) | 2008-04-16 | — | — | EP | disclosed |
| US-20080038181-A1 | Alkaline-Earth Metal Carbonate Core Coated With at Least One Group IV Transition Metal Compound | SOLVAY(SOCIETE ANONYME) (BE) | 2008-02-14 | — | — | US | disclosed |
| EP-1773719-A2 | ALKALINE - EARTH METAL CARBONATE CORE COATED WITH AT LEAST ONE GROUP IV TRANSITION METAL COMPOUND | SOLVAY INTEROX (Société Anonyme) (BE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2007021472-A2 | PROCESS FOR PREPARATION OF CATALYST CARRIER AND ITS USE IN CATALYST PREPARATION | SD LIZENZVERWERTUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007021473-A2 | PROCESS FOR PREPARATION OF A CATALYST CARRIER | SD LIZENZVERWERTUNGSGESELLSCHAFT MBH & CO. KG (DE) | 2007-02-22 | — | — | WO | disclosed |
| WO-2006010754-A2 | ALKALINE-EARTH METAL CARBONATE CORE COATED WITH AT LEAST ONE GROUP IV TRANSITION METAL COMPOUND | Solvay (Société Anonyme) (BE) | 2006-02-02 | — | — | WO | disclosed |
| EP-1621519-A1 | Alkaline - earth metal carbonate core coated with at least one Group IV transition metal compound | SOLVAY (Société Anonyme) (BE) | 2006-02-01 | — | — | EP | disclosed |
| US-6252095-B1 | GOLD PARTICLES ON SUPPORT | DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2001-06-26 | — | — | US | disclosed |
| EP-1040869-A2 | Gold-containing catalyst and method of manufacturing epoxide using the same | Nippon Shokubai Co., Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
| EP-1005907-A1 | CATALYST FOR PARTIALLY OXIDIZING UNSATURATED HYDROCARBON | Japan as represented by Director-General, Agency of Industrial Science and Technology (JP) | 2000-06-07 | — | — | EP | disclosed |