SCHEMBL3798142

SCHEMBL3798142

CCCCCCCCCCCC(CC(CCCCCCCCC)C(=O)O)C(=O)O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.78
GRIK2 Q13002 3/20 0.78
SLC1A2 P43004 3/20 0.74
SLC1A1 P43005 3/20 0.74
SLC1A3 P43003 2/20 0.64
CA2 P00918 2/20 0.64
MAPK1 P28482 1/20 0.64
GPR84 Q9NQS5 6/20 0.61
FFAR1 O14842 1/20 0.61
MAPT P10636 1/20 0.59
LCK P06239 1/20 0.59
PPARD Q03181 1/20 0.59
ZDHHC20 Q5W0Z9 1/20 0.59
ZDHHC2 Q9UIJ5 1/20 0.59
ACE2 Q9BYF1 1/20 0.55
CHRM1 P11229 1/20 0.54
AKR1A1 P14550 1/20 0.54
CHRM3 P20309 1/20 0.54
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17785976 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL8034530 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL2502978 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL577908 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL1197864 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL6032768 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL6898445 1.00 GRIK1 (0.78) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL4843975 0.98 GRIK1 (0.75) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL83876 0.98 GRIK1 (0.77) GRIK1GRIK2SLC1A2SLC1A1SLC1A3
SCHEMBL88213 0.98 GRIK1 (0.77) GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070275433-A1 Cells Containing a Nanopatch Sensor in Their Membrane BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2007-11-29 US claimed
EP-1671123-A1 CELLS CONTAINING A NANOPATCH SENSOR IN THEIR MEMBRANE Ben-Gurion University of the Negev Research and Development Authority (IL) 2006-06-21 EP claimed
WO-2005031348-A1 CELLS CONTAINING A NANOPATCH SENSOR IN THEIR MEMBRANE- BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2005-04-07 WO claimed
US-7855073-B2 Cells containing a nanopatch sensor in their membrane BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2010-12-21 US disclosed
US-20080299598-A1 Detector Comprising a Membrane Perturbation - Detecting Polymer and Functional Membrane Fragments BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2008-12-04 US disclosed
US-20070275433-A1 Cells Containing a Nanopatch Sensor in Their Membrane BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2007-11-29 US disclosed
EP-1671123-A1 CELLS CONTAINING A NANOPATCH SENSOR IN THEIR MEMBRANE Ben-Gurion University of the Negev Research and Development Authority (IL) 2006-06-21 EP disclosed
WO-2006046229-A2 A DETECTOR COMPRISING A MEMBRANE PERTURBATION - DETECTING POLYMER AND FUNCTIONAL MEMBRANE FRAGMENTS BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2006-05-04 WO disclosed
WO-2005031348-A1 CELLS CONTAINING A NANOPATCH SENSOR IN THEIR MEMBRANE- BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2005-04-07 WO disclosed