Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2496582 | 0.88 | EGLN1 (0.67) | EGLN1HIF1A | |
| SCHEMBL2500250 | 0.80 | EGLN1 (0.62) | EGLN1HIF1A | |
| SCHEMBL2499653 | 0.77 | EGLN1 (0.59) | EGLN1HIF1A | |
| SCHEMBL2498503 | 0.77 | EGLN1 (0.59) | EGLN1HIF1A | |
| SCHEMBL2493998 | 0.77 | EGLN1 (0.59) | EGLN1HIF1A | |
| SCHEMBL2493231 | 0.77 | EGLN1 (1.00) | EGLN1HIF1A | |
| SCHEMBL2496588 | 0.76 | EGLN1 (0.57) | EGLN1HIF1A | |
| SCHEMBL2500286 | 0.75 | EGLN1 (0.54) | EGLN1HIF1A | |
| SCHEMBL2493990 | 0.75 | EGLN1 (0.56) | EGLN1HIF1A | |
| SCHEMBL2502458 | 0.75 | EGLN1 (0.64) | EGLN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150251-A1 | THIENOPYRIDINE AND THIAZOLOPYRIDINE DERIVATIVES THAT INHIBIT PROLYL HYDROXYLASE ACTIVITY | Amgen, Inc (US) | 2010-02-10 | — | — | EP | claimed |
| WO-2008137060-A1 | THIENOPYRIDINE AND THIAZOLOPYRIDINE DERIVATIVES THAT INHIBIT PROLYL HYDROXYLASE ACTIVITY | AMGEN INC. (US) | 2008-11-13 | — | — | WO | claimed |