Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 20/20 | 0.58 |
| ▸ | SLC5A1 | P13866 | 14/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | SLC5A11 | Q8WWX8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551779 | 1.00 | SLC5A2 (0.58) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL1551453 | 1.00 | SLC5A2 (0.58) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL13083163 | 1.00 | SLC5A2 (0.58) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL18466486 | 0.95 | SLC5A2 (0.53) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL15680698 | 0.94 | SLC5A2 (0.52) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL15680868 | 0.92 | SLC5A2 (0.50) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL3684426 | 0.90 | SLC5A2 (0.47) | SLC5A2SLC5A1 | |
| SCHEMBL3680743 | 0.90 | SLC5A2 (0.47) | SLC5A2SLC5A1 | |
| SCHEMBL15680703 | 0.90 | SLC5A2 (0.51) | SLC5A2SLC5A1ADRA2ASLC5A11 | |
| SCHEMBL15680798 | 0.89 | SLC5A2 (0.50) | SLC5A2SLC5A1ADRA2ASLC5A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2324002-B1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOS SUB LLC (US) | 2016-10-05 | — | — | EP | disclosed |
| EP-2324002-B1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOS SUB LLC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-9006403-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006403-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006403-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130046088-A1 | Processes for the Preparation of SGLT2 Inhibitors | THERACOS, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20130046088-A1 | Processes for the Preparation of SGLT2 Inhibitors | THERACOS, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-20130046088-A1 | Processes for the Preparation of SGLT2 Inhibitors | THERACOS, INC. (US) | 2013-02-21 | — | — | US | disclosed |
| US-8283454-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283454-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283454-B2 | Processes for the preparation of SGLT2 inhibitors | THERACOS, INC. (US) | 2012-10-09 | — | — | US | disclosed |
| US-20100222599-A1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOSBIO, LLC | 2010-09-02 | — | — | US | disclosed |
| US-20100222599-A1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOSBIO, LLC | 2010-09-02 | — | — | US | disclosed |
| US-20100222599-A1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOSBIO, LLC | 2010-09-02 | — | — | US | disclosed |
| WO-2010022313-A2 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | THERACOS, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222599-A1 | PROCESSES FOR THE PREPARATION OF SGLT2 INHIBITORS | SLC5A2, SLC5A1, SLC2A4 | SLC5A2 1/4885SLC5A1 2/4885ADRA2A 1802/4885 |
| US-20130046088-A1 | Processes for the Preparation of SGLT2 Inhibitors | SLC5A2, SLC5A1, SLC2A4 | SLC5A2 1/4885SLC5A1 2/4885ADRA2A 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.