Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.67 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.51 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.50 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2673812 | 1.00 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2673391 | 1.00 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2673176 | 0.95 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674753 | 0.91 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674756 | 0.91 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2673299 | 0.91 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674091 | 0.90 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674089 | 0.89 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674834 | 0.89 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674086 | 0.89 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138589-A1 | BICYCLIC PYRIMIDINE PI3K INHIBITOR COMPOUNDS SELECTIVE FOR P110 DELTA, AND METHODS OF USE | GENENTECH, INC. (US) | 2010-12-02 | — | — | WO | disclosed |