Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605518 | 0.96 | MAPT (0.38) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL535361 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTALDH1A1LMNAKDM4E | |
| SCHEMBL535165 | 0.81 | MAPT (0.35) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL535164 | 0.81 | MAPT (0.35) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534845 | 0.79 | MAPT (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534678 | 0.79 | MAPT (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534844 | 0.79 | MAPT (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534677 | 0.79 | MAPT (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534843 | 0.79 | MAPT (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 | |
| SCHEMBL534540 | 0.79 | HSD17B10 (0.36) | SMN1; SMN2NPSR1MAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139324-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | Syngeta Participations AG (CH) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008110355-A1 | QUINOLINE DERIVATIVES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |